Results 121 to 130 of about 21,832,942 (335)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Classical -Quantum Multiple Access Channel with Secrecy Constraint: One-shot Rate Region
International Journal of Information and Communication Technology Research, 2020 In this paper, we aim to study a -user quantum multiple access wiretap channel with an arbitrary number of wiretappers under one-shot setting. In this regard, we first introduce the general quantum multiple access wiretap channel and the simplified ...
Hadi Aghaee, Bahareh Akhbari
doaj
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Activated seismicity by strain rate change in the Yaeyama region, south Ryukyu
Earth, Planets and Space, 2018 We evaluated the long-term strain rate by using continuous global navigation satellite system data of GEONET and compared it with seismicity activation between 1996 and 2017 near Iriomote Island, south Ryukyu arc.
Mamoru Nakamura, Ayumi Kinjo
doaj +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Critical region within 22q11.2 linked to higher rate of autism spectrum disorder
Molecular Autism, 2017 Background Previous studies have reported no clear critical region for medical comorbidities in children with deletions or duplications of 22q11.2. The purpose of this study was to evaluate whether individuals with small nested deletions or duplications ...
Caitlin C. Clements +12 more
doaj +1 more source
The rate-distortion region for multiple descriptions without excess rate [PDF]
IEEE Transactions on Information Theory, 1985 During recent years there has been strong interest in a certain source coding problem, which some authors call the ''problem of multiple descriptions. Old and new wringing techniques enable us to establish a single-letter characterization of the rate-distortion region in the case of no excess rate for the joint description.
openaire +2 more sources
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
The current bovine leukemia spread situation in the Russian Federation
Ветеринария и кормлениеLeukemia is a common, untreatable chronic infectious cattle disease, causing significant losses to the agricultural sector of the economy of many countries, including the Russian Federation.
Donnik I.M. +5 more
doaj +1 more source