Results 121 to 130 of about 1,145,386 (265)

Prehospital assessment of perinatal patients by ambulance clinicians: development, implementation, review and national application. [PDF]

Int J Emerg Med
Main C, Shaw J, Burgess L, Heys S, Rhind S, Kelly T.   +5 more
europepmc   +1 more source

Association between the number of oocytes retrieved, cancellation rates, and clinical outcomes in IVF PGT cycles with single embryo transfer (SET) - a 2273 cycles review [PDF]

Fertility and Sterility, 2019
Oleksii O. Barash, Kristen Ivani, Mary D. Hinckley, Louis N. Weckstein   +3 more
openaire   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Increase in imported mupirocin-resistant <i>Staphylococcus aureus</i> from the tropics and subtropics: trends in Berlin from 2018 to 2025. [PDF]

New Microbes New Infect
Moreno-Del Castillo MC, Humme D, Leistner R, Krüger R, Stegemann M, Hanitsch L, Layer-Nicolaou F, Knaust A, Sägmüller JG, Stein A, Pitzinger P, Hucko A, Rohmann JL, Mockenhaupt FP, Kampmann B, Nurjadi D, Zanger P, Lindner AK.   +17 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Research and Development of Cement-Based Dynamic Water Grouting Material for the CSM Construction Method. [PDF]

Materials (Basel)
Yang Z, Zhang F, Chang Y, Yang X, Li J, Feng Q, Wang H, Tong H.   +7 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Divergent regulation of rice yield by carbon nanomaterials via biomass allocation and seed setting rate. [PDF]

Front Plant Sci
Ma Y, Chen H, Tian Z, Wang R, Sun Z, Li T, Zhang M, Wang Y.   +7 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Social determinants of health screening and interventions in neonatal care pathways (NICU to follow-up): a scoping review. [PDF]

Eur J Pediatr
Nezafat Maldonado B, Evans K, Jones M, Park J, Wood E, Khan H, Cawley P.   +6 more
europepmc   +1 more source