Results 181 to 190 of about 1,145,386 (265)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

A systematic review and meta-analysis of the impact of relaxation techniques to reduce burden of disease in patients with psychotic disorders. [PDF]

Sci Rep
Schlößer N, Theisen C, Meisenzahl E, Kieckhäfer C.   +3 more
europepmc   +1 more source

Outcomes of Cross-Leg Flap Use in Lower Limb Salvage in Resource-Limited Settings: A Systematic Review of Indications, Limitations, and Success Rates

Cureus
Ibrahim, Abdelrahman, Mohamed Farahat, Sherif, Dahy, Bassant, Shehata Abdelmesih, Shenouda, Sahnon Abaker Sahnon, Abdelrahman, Hamadelniel Alhadi, Ibrahim Adil, Humida Ali Gorashi, Gorashi, H. J. Alkhazendar, Jarallah, Alkhazendar, Aliaa H, Ahmad, Shahzad   +9 more
openaire   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Physiological Responses to Virtual Reality-Based Stress Regulation and Relaxation Interventions: A Systematic Review. [PDF]

Stress Health
Robbemond LM, Noordzij ML, van Driel CMG, Veling W.   +3 more
europepmc   +1 more source

Can Anterior Discectomy and Fusion (ACDF) Surgery be Safely Performed in an Outpatient Setting? A Systematic Review on the Post-operative Complication and Readmission Rates

Journal of Spine Research and Surgery
Salman Ghani BEng, MSc, MBBS, Ahmed Ali Kayyale MBBS   +1 more
openaire   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Annual Review of Systemic Medical Treatment for Colorectal Cancer in 2025. [PDF]

Cancer Innov
Cai Z, Chen F, Jin Y, Wang F.
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Interventions Promoting Work Engagement and Reducing Turnover of Newly Graduated Nurses: A Systematic Review. [PDF]

Nurs Open
Al-Hello L, Ervasti J, Haapa T, Sorsa VP, Melender HL.   +4 more
europepmc   +1 more source