Results 231 to 240 of about 13,243,531 (353)

Faculty Opinions recommendation of The rate of the molecular clock and the cost of gratuitous protein synthesis.

, 2010
Joshua B. Plotkin
openalex   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Increases in Kratom-Related Reports to Poison Centers - National Poison Data System, United States, 2015-2025.

MMWR Morb Mortal Wkly Rep
Towers EB, Thomas YT, Holstege CP, Farah R.   +3 more
europepmc   +1 more source

Comparative Analysis of Flight Volume Effects on COVID-19 and Influenza Transmission Across Variable Control Intensities, 2019-2024. [PDF]

J Infect Dis
Xu Y, Li M, Peng L, Wang C, Wan Q, Zhang C, Xiong W, Yang B, Tsang TK.   +8 more
europepmc   +1 more source

Railroad Rates [PDF]

Science, 1935
openaire   +2 more sources

Welsh Government Consultation : Charitable rates relief for schools and hospitals in Wales [PDF]

, 2020

core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Incidence of toxic anterior segment syndrome and endophthalmitis in 190 000 eyes in a high-volume, multisurgeon, national network of ambulatory surgical centers using uniform perioperative protocols. [PDF]

J Cataract Refract Surg
Wallerstein A, Lekhi V, Ahmed IK, Harissi-Dagher M, Albert D, Lloyd J, Racine L, Trottier P, Cohen M, Gauvin M.   +9 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Non-fatal drug overdose surveillance using hospital discharge data: a comparison between the Drug Overdose Surveillance and Epidemiology (DOSE) system and the Healthcare Cost and Utilisation Project, 18 states, 2018-2020. [PDF]

Inj Prev
Quader ZS, Park J, Krishnan SD, Stokes E, Pickens CM.   +4 more
europepmc   +1 more source