Results 231 to 240 of about 957,800 (264)

Quality Evaluation Using the Mobile App Rating Scale for Speech Therapy in Parkinson Disease: Systematic Search and Evaluation. [PDF]

JMIR Form Res
Haris T, Shah H, Florez-Arango JF.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Breathe, Eat, Talk: Three Essential Ingredients to Quality-of-Life Outcomes in Movement Disorders. [PDF]

Mov Disord Clin Pract
Dean J, O'Flynn LC, Ciucci M, Fox C, Huber JE, Anand S, Olchik MR, Usman JS, Vogel AP, Aguiar B, Khasanova D, Manoharan D, Ramig L, Roberts A, Rodriguez-Porcel F, Simonyan K, Barkmeier-Kraemer JM.   +16 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Consistency of Judging Under the World Boxing 10-Point Must Scoring System: Single-Judge and Five-Judge Aggregate Reliability Across the 60 kg, 75 kg, and 90+ kg Categories at the 2025 World Boxing Championships. [PDF]

Sports (Basel)
Munda G, Kuvačić G, Besal S, Karpljuk D, Batista M, Rydzik Ł, Šimenko J.   +6 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Mapping online patient reviews onto a data-informed service-experience framework: a content analysis of tertiary hospitals in Wuxi, China. [PDF]

Front Public Health
Xia T, Tian W, Li L, Zhang Y, Zhou Y, Li S, Shao Y, Wang J.   +7 more
europepmc   +1 more source

Acute Haemodynamic and Perceptual Responses to Graded Intradialytic Exercise in Patients on Maintenance Haemodialysis: A Randomised Crossover Trial. [PDF]

J Ren Care
Hmida M, Abouzida MA, Bardiaa Y, Abed KE.   +3 more
europepmc   +1 more source

Judgment behaviors differentiate depression from anxiety. [PDF]

Sci Rep
Vike NL, Bari S, Strawn JR, Zhan F, Kim B, Breiter HC.   +5 more
europepmc   +1 more source

Observing teaching principles in school - Development and Validation of an Observation Protocol (OPTIS). [PDF]

PLoS One
Mühlberg T, Bachner J, Mess F, Schmid-Ellinger J.   +3 more
europepmc   +1 more source