Results 91 to 100 of about 45,639 (357)

Effect of 4 weeks ischemic preconditioning on VEGF, lactate response and fatigue index after intensive exercise

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2020
Background and Objective: Acute ischemic preconditioning improves exercise performance. This study was done to determine the effect of four weeks of ischemic preconditioning on vascular grow factor (VEGF), lactate metabolism and fatigue indices. Methods:
Amin Farzaneh Hesari
doaj  

The Validation of Session Rating of Perceived Exertion for Quantifying Internal Training Load in Adolescent Distance Runners.

open access: yesInternational Journal of Sports Physiology and Performance, 2019
PURPOSE To investigate the effect of measurement timing and concurrent validity of session and differential ratings of perceived exertion (sRPE and dRPE, respectively) as measures of internal training load in adolescent distance runners.
Robert H Mann   +3 more
semanticscholar   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

Foam Rolling Intervention Improves Lactate Clearance After High-Intensity Exercise

open access: yesSports
The acute effects of a foam rolling intervention on lactate clearance and the impaired executive function associated with fatigue after high-intensity exercise remain unclear.
Kazuki Kasahara   +4 more
doaj   +1 more source

Effects of caffeine on time to exhaustion in exercise performed below and above the anaerobic threshold

open access: yesBrazilian Journal of Medical and Biological Research, 1998
Controversy still exists concerning the potential ergogenic benefit of caffeine (CAF) for exercise performance. The purpose of this study was to compare the effects of CAF ingestion on endurance performance during exercise on a bicycle ergometer at two ...
B.S. Denadai, M.L.D.R. Denadai
doaj   +1 more source

Consistency of pacing and metabolic responses during 2000-m rowing ergometry [PDF]

open access: yes, 2013
PURPOSE: This study investigated the pacing strategy adopted and the consistency of performance and related physiological parameters across three 2000-m rowing-ergometer tests. METHODS: Fourteen male well-trained rowers took part in the study.
French, Duncan N.   +3 more
core   +2 more sources

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Session RPE Breakpoints Corresponding to Intensity Thresholds in Elite Open Water Swimmers

open access: yesJournal of Functional Morphology and Kinesiology, 2020
This study aims to assess the correspondence between session rating of perceived exertion (sRPE) breakpoints with both the first lactate threshold (LT1) and the second lactate threshold (LT2) in elite open water swimmers (OWS).
Cristian Ieno   +4 more
doaj   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Pupils’ and teachers’ experiences of school-based physical education: A qualitative study [PDF]

open access: yes, 2014
Objectives: To explore pupils’ and teachers’ experiences of P.E. Study Design: A qualitative investigation employing semi-structured interviews. Self Determination Theory was used as a guiding theory and Template Analysis was used to analyse the data.
Belton   +26 more
core   +1 more source

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