Results 101 to 110 of about 45,639 (357)

The Sensitivity of Differential Ratings of Perceived Exertion as Measures of Internal Load [PDF]

International Journal of Sports Physiology and Performance, 2016
Purpose:To investigate the sensitivity of differential ratings of perceived exertion (dRPE) as measures of internal load.Methods:Twenty-two male university soccer players performed 2 maximal incremental-exercise protocols (cycle, treadmill) on separate days.
McLaren, SJ, Graham, M, Spears, IR, Weston, M   +3 more
openaire   +5 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Higher rating of perceived exertion and lower perceived recovery following a graded exercise test during menses compared to non-bleeding days in untrained females

Frontiers in Physiology
The underrepresentation of the female population in exercise sciences could be attributed, at least in part, to difficulty in appropriately accounting for the effects of the menstrual cycle (MC).
Morgan Delp, Grant A. Chesbro, Brian A. Pribble, Ryan M. Miller, Hugo M. Pereira, Christopher D. Black, Rebecca D. Larson   +6 more
doaj   +1 more source

Agreement between session RPE and individual training impulse across a range of running speeds [PDF]

, 2016
BACKGROUND: The training impulse (TRIMP) provides a means of quantifying training dose during physical training; it is traditionally based on the heart rate response to exercise and involves establishing the heart rate – blood lactate relationship. A new
Curtis, Ffion, Thatcher, Rhys
core  

Inspiratory muscle training and its effect on indices of physiological and perceived stress during incremental walking exercise in normobaric hypoxia [PDF]

, 2014
This study evaluated the effects of inspiratory muscle training (IMT) on inspiratory muscle fatigue (IMF) and physiological and perceptual responses during trekking-specific exercise. An 8-week IMT program was completed by 21 males (age 32.4 ± 9.61 years,
Bartesaghi, M, Celegato, Barbara, Giardini, G, Lanfranchi, Gerolamo, Laveder, Paolo, Malacrida, S, Millino, Caterina, Pacchioni, Beniamina, Pratali, L   +8 more
core   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

WEEKLY PROFILE OF TRAINING LOAD AND RECOVERY IN ELITE RHYTHMIC GYMNASTS

Science of Gymnastics Journal, 2019
The aim of this study is to analyze the weekly profile of internal training load (ITL) and recovery of elite rhythmic gymnasts during a season. Eight professional rhythmic gymnasts of the Brazilian senior group participated.
Paula Debien , Bernardo Miloski, Thiago Timoteo, Camila Ferezin , Maurício Bara Filho   +4 more
doaj   +1 more source

High intensity intermittent running and field hockey skill performance in the heat [PDF]

, 2005
Nine well-trained, unacclimatized female hockey players performed the Loughborough Intermittent Shuttle Test (LIST) interspersed with three field hockey skill tests in hot (30°C, 38% relative humidity) and moderate (19°C, 51% relative humidity ...
Nevill, ME, Sunderland, C
core   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Relationship between External Load and Perceptual Responses to Training in Professional Football: Effects of Quantification Method

Sports, 2019
We examined the within-player correlation between external training load (ETL) and perceptual responses to training in a professional male football team (n = 13 outfield players) over an eight-week competitive period.
Vincenzo Rago, João Brito, Pedro Figueiredo, Peter Krustrup, António Rebelo   +4 more
doaj   +1 more source