From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan+2 more
wiley +1 more source
Beta-Alanine Supplementation for CrossFit® Performance
This study aimed to investigate whether beta-alanine supplementation (BA) improves performance and rating of perceived exertion (RPE) and reduces the respiratory exchange ratio (RER) during a CrossFit® workout.
Hannah Verity+2 more
doaj +1 more source
The Effects of Men\u27s Lacrosse Protective Equipment on Thermoregulation and Perceptions During Exercise Heat Stress [PDF]
The effects of men\u27s lacrosse protective equipment on thermoregulation and perceptions during exercise heat stress Amanda P. Glasgow: Exercise Science Research Center, University of Arkansas, Fayetteville, AR.
Glasgow, Amanda
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Attentional distraction during exercise in overweight and normal-weight boys [PDF]
The purpose of this study was to investigate the effect of attentional distraction on field running distance and activity intensity during an exercise session in normal-weight and overweight youngsters and to investigate potential mediators.
De Bourdeaudhuij, Ilse+1 more
core +2 more sources
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen+2 more
wiley +1 more source
The present study investigated the effect of unilateral and bilateral resistance exercise (RE) on maximal voluntary strength, total volume of load lifted (TVLL), rating of perceived exertion (RPE) and blood lactate concentration of resistance-trained ...
Eduardo C Costa+4 more
doaj +1 more source
Effect of suspension systems on the physiological and psychological responses to sub-maximal biking on simulated smooth and bumpy tracks [PDF]
The aim of this study was to compare the physiological and psychological responses of cyclists riding on a hard tail bicycle and on a full suspension bicycle. Twenty males participated in two series of tests. A test rig held the front axle of the bicycle
Arthur Whittaker+11 more
core +1 more source
PURPOSE The aim of the current study was to identify the external-training-load markers that are most influential on session rating of perceived exertion (RPE) of training load (RPE-TL) during elite soccer training.
P. Gaudino+6 more
semanticscholar +1 more source
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan+2 more
wiley +1 more source
The use of heart rate indices and subjective questionnaires in the determination of fatigue in motor-manual tree felling and delimbing operations in New Zealand exotic plantation forests : a thesis presented in partial fulfilment of the requirements for the degree of Master of Business Studies in Ergonomics at Massey University [PDF]
This study assessed the use of heart rate indices and subjective questionnaires in the determination of fatigue in motor-manual tree felling operations in New Zealand exotic plantation forests. The research design consisted of a causal study utilising an
Kirk, Patrick Michael
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