Results 101 to 110 of about 1,790,394 (354)
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock+10 more
wiley +1 more source
Variations in Rating Scale Functioning In Assessing Pragmatic Performance in L2 Chinese [PDF]
Adopting Linacre’s guidelines for evaluating rating scale effectiveness, we examined whether and how a six-point rating scale functioned differently across raters, speech acts, and second language (L2) proficiency levels.
Li, Shuai, Taguchi, Naoko, Xiao, Feng
core +1 more source
Smoothing Before Estimating Uncertainty, Scaling, and Intermittency: Application to Short Heart Rate Signals [PDF]
Three aspects of time series are uncertainty (dispersion at a given time scale), scaling (time-scale dependence), and intermittency (inclination to change dynamics). Simple measures of dispersion are the mean absolute deviation and the standard deviation; scaling exponents describe how dispersions change with the time scale.
arxiv
Besides teachers' professional knowledge, their self-efficacy is a crucial aspect in promoting students' scientific reasoning (SR). However, because no measurement instrument has yet been published that specifically refers to self-efficacy beliefs ...
Virginia Deborah Elaine Welter+3 more
doaj +1 more source
Assessing Spoken EFL Without a Common Rating Scale
This study investigated teacher cognition and behavior in a high-stakes, English as a Foreign Language (EFL) school context where no common rating scale exists.
Henrik Bøhn
doaj +1 more source
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar+4 more
wiley +1 more source
The Effects of Training and Rating Formats on the Accuracy of Performance Ratings [PDF]
The effects of frame of reference training and rating formats on the accuracy of performance ratings were examined utilizing direct measures of accuracy in addition to commonly used measures of rating biases.
Silverhart, Todd A.
core +1 more source
Improving Low Bit-Rate Video Coding using Spatio-Temporal Down-Scaling [PDF]
Good quality video coding for low bit-rate applications is important for transmission over narrow-bandwidth channels and for storage with limited memory capacity. In this work, we develop a previous analysis for image compression at low bit-rates to adapt it to video signals.
arxiv
This research develops a multicriteria rating scale for the assessment of oral presentations in language for specific purposes (LSP) in order to make the assessment process easier, more objective, and reliable.
Vesna M. Petrović+2 more
doaj +1 more source