Results 141 to 150 of about 1,790,394 (354)

When less is more: validating a brief scale to rate interprofessional team competencies

open access: yesMedical Education Online, 2017
Background: There is a need for validated and easy-to-apply behavior-based tools for assessing interprofessional team competencies in clinical settings.
Désirée A. Lie   +4 more
doaj   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

open access: yesMolecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh   +6 more
wiley   +1 more source

Rotational effects on the small-scale dynamo [PDF]

open access: yesarXiv
Using direct numerical simulations of forced rotating turbulence, we study the effect of rotation on the growth rate and the saturation level of the small-scale dynamo. For slow rotation rates, increasing the rotation rate reduces both the growth rate and the saturation level.
arxiv  

How to assess communication skills? Development of the rating scale ComOn Check: Evaluation of communication skills

open access: yesMedical Education Online, 2017
Background: Good communication is a core competency for all physicians. Thus, medical students require adequate preparation in communication skills.
K. Radziej   +9 more
doaj   +1 more source

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

open access: yesMolecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan   +6 more
wiley   +1 more source

Specification and Estimation of Rating Scale Models: With an Application to the Determinants of Life Satisfaction [PDF]

open access: yes
Rating variables indicate the extent to which a quality is present, or absent, in a unit of observation. In this paper, we discuss a class of non-linear regression models for rating dependent variables and their estimation by parametric and ...
Rainer Winkelmann, Raphael Studer
core  

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

open access: yesMolecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song   +13 more
wiley   +1 more source

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