Results 71 to 80 of about 452,911 (267)
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Frontiers in Psychology, 2019 Mixture models of item response theory (IRT) can be used to detect inappropriate category use. Data collected by panel surveys where attitudes and traits are typically assessed by short scales with many response categories are prone to response styles ...
Tanja Kutscher +3 more
doaj +1 more source
Use of global rating scales and checklists in clinical simulation-based assessments: a protocol for a scoping review [PDF]
, 2023 Karien Henrico, Andrew William Makkink
openalex +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Industria: Jurnal Teknologi dan Manajemen Agroindustri, 2013 Abstrak Tujuan dari penelitian ini yaitu mendapatkan bobot kriteria kompetensi dengan metode ANPdan mendapatkan hasil penilaian kinerja karyawan dengan menggunakan rating scale.AnalyticNetwork Process (ANP) merupakan salah satu metode yang dapat ...
Tenny Sylvia +2 more
doaj
Mood versus energy/activity symptoms in bipolar disorder: which cluster of Hamilton Depression Rating Scale better distinguishes between mania, depression, and euthymia? [PDF]
, 2019 Elie Cheniaux +4 more
openalex +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Utilizing the Menopause Rating Scale questionnaire in electronic form for evaluating the quality of life in postmenopausal women [PDF]
, 2017 Markéta Moravcová, Jana Holá
openalex +1 more source