Incremental Prognostic Information Beyond Nodal Positivity: The AJCC 8th Edition N1/N2 Subdivision and the Lymph Node Ratio in Resected Periampullary Adenocarcinoma. [PDF]
Na GH, Seo C.
europepmc +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Distinct Bone Turnover Alterations Across Glycemic Phenotypes of Type 2 Diabetes and the Role of a Comprehensive Nutritional Index in Postmenopausal Women. [PDF]
Choi JW, Fujii N, Fujii T.
europepmc +1 more source
Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani +7 more
wiley +1 more source
Comparative Assessment of Commercial and Waste-Derived Sodium Silicate Activators in PFA-GGBS Alkali-Activated Concrete. [PDF]
Ayres A, Oti J, Kinuthia J.
europepmc +1 more source
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source
Spontaneous Reduction in Mitral Valve Regurgitation in Three Dogs With Severe Myxomatous Mitral Valve Disease: An Unusual Case Report. [PDF]
Nam HS, Oh Y.
europepmc +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
A Two-Tier Patient-Based Real-Time Quality Control Program Integrating K-Means Department Stratification and Inter-Instrument Ratios Improves Detection of Small Systematic Errors in Creatinine Testing. [PDF]
Wei X +7 more
europepmc +1 more source

