Results 251 to 260 of about 34,945,907 (346)

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Simulation of liquid hydrocarbon production via n-tetradecane reforming: A renewable energy approach. [PDF]

PLoS One
Farajzadeh A, Bahadori F.
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Femoral radiographic indices for pre-operative osteoporosis screening in postmenopausal female patients undergoing total hip arthroplasty for osteoarthritis. [PDF]

PLoS One
Nishi M, Yoshikawa Y, Usui Y, Nishida H, Nakamura S, Tashiro K, Kudo Y.   +6 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Metastasis number and ratio in regional lymph nodes as predictive indicators for distant metastasis in medullary thyroid cancer: beyond American Joint Committee on Cancer nodal staging. [PDF]

Gland Surg
Chen Z, Su J, Li N, Xia W.
europepmc   +1 more source

Clinical Analysis of Peripheral Blood Indicators for Immune-Related Adverse Events (irAEs) in Patients With Advanced Lung Cancer. [PDF]

Clin Med Insights Oncol
Ji YM, Qin YH, Lv YH, Xiao SY, Dong Y, Hu ZS, Cui PF, Li T, Cui XR, Hu Y.   +9 more
europepmc   +1 more source

Pancreatitis induced by Peg-aspargase in children: a real-world pharmacovigilance analysis based on FDA Adverse Event Reporting System (FAERS). [PDF]

Leuk Res Rep
Zhang W, Luo B, Liu Z, Mi J, Yang Y, Li Y.   +5 more
europepmc   +1 more source