Results 101 to 110 of about 2,014 (239)
Advanced Science, EarlyView.A biotin‐modified artificial insertion peptide functionalized three‐dimensional high‐curvature‐TiO2 nano‐interface was engineered in a microfluidic chip to improve the isolation efficiency of small extracellular vesicles (sEVs). This chip balanced affinity, releasability, and extendibility, enabling high‐throughput recovery of sEVs for downstream ...
Le Wang +7 more
wiley +1 more source
Singular locus of rational ruled surfaces
, 2001 We prove that the morphism that maps a rational ruled surface to its singular locus is genericaly injective modulo isomophism and duality. We also calculate the dimension and the degre of its image.
openaire +2 more sources
Advanced Science, EarlyView.THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu +10 more
wiley +1 more source
Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy
Advanced Science, EarlyView.Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu +4 more
wiley +1 more source
Ruled and rational surfaces and their models
One of the most powerful ideas in the study and classification of algebraic varieties is the notion of a model: that is, to single out an object, in the appropriate isomorphism class, with nice properties. This survey aims to define and study suitable models of rational and, more generally, ruled surfaces in the smooth complex case, and to use them to ...
openaire +2 more sources
Strange Duality on Rational Surfaces II: Higher-Rank Cases
, 2018 We study Le Potier’s strange duality conjecture on a rational surface. We focus on the strange duality map $SD_{c_n^r,L}$ that involves the moduli space of rank $r$ sheaves with trivial 1st Chern class and 2nd Chern class $n$, and the moduli space of one-
Yao Yuan
core +1 more source
Advanced Science, EarlyView.This study identifies that methylglyoxal may play an important role in heart‐brain interactions after myocardial infarction. Myocardial infarction leads to increased levels of methylglyoxal‐derived advanced glycation end‐products (MG‐H1) in the brain of mice, which is associated with loss of blood‐brain barrier integrity and neuroinflammation ...
Ramis Ileri, Xixi Guo, Erik J. Suuronen
wiley +1 more source
Advanced Science, EarlyView.Whole‐genome analysis of 1,054 chickens reveals three ancestral sources (NWC, SYA, and SHF) with distinct temporal entry patterns into the Tibetan Plateau. Route‐specific selection scans, calibrated against a demographic null, suggest complementary functional enrichments—vascular homeostasis (NWC), calcium signaling and cardiac adaptation (SYA), and ...
Zongyi Zhao +7 more
wiley +1 more source
Algebraic Homology For Real Hyperelliptic and Real Projective Ruled Surfaces
, 2001 Let X be a reduced nonsingular quasiprojective scheme over such that the set of real rational points X() is dense in X and compact. Then X() is a real algebraic variety.
Miguel A. Abánades
core +1 more source
ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals
Advanced Science, EarlyView.The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray +3 more
wiley +1 more source