Results 181 to 190 of about 1,132,202 (287)
Blood SOD1 Activity in ALS Patients Receiving Tofersen Treatment
Annals of Neurology, EarlyView.Objective The antisense oligonucleotide tofersen is the first disease‐modifying drug for SOD1‐related amyotrophic lateral sclerosis (ALS) and was approved because of its ability to reduce SOD1 protein and neurofilament levels. The effect of tofersen on SOD1 activity is unclear but of clinical relevance because homozygous SOD1 mutations, linked to ...
Katharina Goehring +18 more
wiley +1 more source
Synthetic microbial communities: emerging live biotherapeutics for targeted gut microbiome modulation. [PDF]
Gut MicrobesZhang R, Li H, Wang C, Yang G.
europepmc +1 more source
Cortical Thickness and White Matter Surface Morphology in Tourette Syndrome: A Cohort Study
Annals of Neurology, EarlyView.Objective To examine cortical thickness and white matter surface morphology in a large sample of individuals with Tourette syndrome (TS) and neurotypical controls across the lifespan, and to assess associations with symptom severity, comorbidities, and medication use.
Sahar Delavari +8 more
wiley +1 more source
A Multi-Model Strategy for Optimizing Hepatitis B Virus preS1 Epitope Recognition by the Antibody HzKR127. [PDF]
Curr Issues Mol BiolChen W +6 more
europepmc +1 more source
Editorial comment on Chinese expert consensus on prostate-pelvic syndrome. [PDF]
Curr UrolKravchick S.
europepmc +1 more source
Background and Objectives: The influence of the quantity and quality of peri-implant soft tissue on implant health and long-term maintenance is controversial.
Eriberto Bressan +5 more
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Thermostability Engineering in Therapeutic Antioxidant Enzymes: From Molecular Fundamentals to Oxidative Stress Applications. [PDF]
Int J Mol SciTatarciuc D +8 more
europepmc +1 more source
DEMOCRATIC LEGITIMACY - Working agreement or rational consensus?
, 2006 The quest for deliberative democracy is connected to the difficulties with what we for the sake of simplicity refer to as a voting model of democracy.1 This model holds elections and votes as the central features of democracy because they establish egalitarian structures of decision-making.
openaire +1 more source
Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy
Angewandte Chemie International Edition, EarlyView.Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean +3 more
wiley +1 more source
: PurposeTo reach consensus among international experts on a structured framework for standardized 3D leg alignment analysis based on 3D bone models, ensuring consistency and improving clinical applicability.MethodsA Delphi study was performed in four ...
Brouwer, Reinoud W. +9 more
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