Results 71 to 80 of about 52,765 (246)

Management of metastatic castration-resistant prostate cancer: Insights from urology experts in Thailand

Prostate International, 2017
Treatment options for castration-resistant prostate cancer (CRPC) are available, but clear instructions for the selection of appropriate treatment are lacking. A meeting of urology experts based in Thailand was convened with the following objectives: (1)
Bannakij Lojanapiwat, Choosak Pripatnanont, Vorapot Choonhaklai, Surithorn Soontornpun, Supon Sriplakich, Sunai Leewansangtong, Apirak Santi-ngamkun, Julin Opanuraks, Wisoot Kongcharoensombat, Bhapapak Na-Songkla, Wiroj Raksakul, Chagkrapan Predanon   +11 more
doaj   +1 more source

Asymmetric Electrostrain/Electrobending in Piezoelectric Ceramics: Role of Defect Dipoles or Oxygen Vacancies

Advanced Science, EarlyView.
Defect‐configurational origins of the asymmetric apparent electrostrain are revealed in different piezoelectric ceramics via atomic‐scale visualization of defect configurations. Migration of oxygen vacancies leads to the electrobending effect in N2‐sintered BaTiO3, while defect dipoles in Ba0.99TiO2.99 generate true asymmetric electrostrain without ...
Jie Wang, Geng Huangfu, Hongjie Zhang, Tiannan Yang, Zhenhua Ma, Jingsheng Chen, Yun Liu, Yiping Guo   +7 more
wiley   +1 more source

Interpretation of the "Expert consensus on the management of neonatal parenteral nutrition (2025)"

中国当代儿科杂志
This article interprets the "Expert consensus on the management of neonatal parenteral nutrition (2025)", focusing on precise control of parenteral nutrition fluid volume, key considerations for the stability of compounded nutrient solutions, scientific ...
LIN Xin-Zhu, ZHANG Rong, CHANG Yan-Mei, LI Zheng-Hong, LIU Xi-Hong, BEI Fei, SHEN Wei, TONG Xiao-Mei, CHEN Chao   +8 more
doaj   +1 more source

Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy

Advanced Science, EarlyView.
MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang, Shengxin Lu, Guangyong Zheng, Shensuo Li, Hongyu Chen, Mei Hong, Xiangru Zhou, Ruotian Tang, Ye Wu, Weidong Zhang, Dong Lu, Xin Luan   +11 more
wiley   +1 more source

How Advanced Artificial Intelligence Technologies Shape Drug–Drug and Drug–Target Interaction Modeling

Advanced Science, EarlyView.
This review explores the convergence of artificial intelligence technologies in modeling drug–drug and drug–target interactions. By evaluating advanced feature engineering, architectural innovations, and learning paradigms reveals shared evolutionary trends and critical challenges, such as cold‐start settings and shortcut learning.
Xin Sun, Tong Wang
wiley   +1 more source

Expert Consensus on Rational Use and Monitoring of Small Molecule Targeted Drugs for Lung Cancer

Chinese Journal of Lung Cancer
The application of small molecule targeted drugs for lung cancer has significantly improved the survival of lung cancer patients. However, these drugs have a wide variety of types, fast development and market launch of new drugs, complex adverse ...
Liyan ZHAO, Kejing TANG, Expert Consensus Working Group on Rational Use and Monitoring of Small Molecule Targeted Drugs for Lung Cancer, Lung Cancer Professional Committee of Guangdong Medical Women’s Association   +3 more
doaj   +1 more source

Expert consensus on the off-label use in China of drugs for rare hematologic diseases (2024 edition)

Frontiers in Pharmacology
Drug package inserts are a crucial foundation for clinical medication practices and serve as the legal basis for guiding rational drug use and ensuring patient safety and efficacy.
Boxin Zhao, Boxin Zhao, Xuan Zhou, Ping Zheng, Ping Zheng, Bo Zhang, Bo Zhang, Xiaoqin Feng, Jie Chen, Lisheng Cai, Yilu Chen, Liya He, Jianfen Su, Shuqin Cheng, Yingtong Zeng, Guowei Li, Bo Ji, Jianlong Wu, Weiyi Feng, Maobai Liu, Yiran Jin, Taotao Liu, Xiaolan Mo, Junyan Wu, Hui Wu, Hongliang Zhang, Zhichang Zheng, Zhihua Zheng, Jing Sun, Yilei Li, Yilei Li, Guangdong Pharmaceutical Association, Hematology Group of Rare Disease Expert Committee of Guangdong Pharmaceutical Association   +31 more
doaj   +1 more source

FOS3D: A Fluorescence‐Enabled Toolkit for Characterizing a Three‐dimensional Osteosarcoma Model

Advanced Science, EarlyView.
FOS3D describes fluorescent (F) osteosarcoma (OS) cells in a tri‐dimensional (3D) model. The study comprises three phases: development, where biofabrication parameters are tuned to achieve cytocompatibility and tumor‐specific mechanical properties in cell‐laden gelatin methacryloyl constructs; validation, where whole‐well fluorescence reading is ...
William Humble, Wiktor Zywicki, Enrico Lucarelli, Ania Naila Guerrieri, Francesca Taraballi, Gianluca Cidonio, Claudia Di Bella, Carmine Onofrillo, Andrea J. O'Connor, Serena Duchi   +9 more
wiley   +1 more source

A short note on the rationality of the false consensus effect [PDF]

, 2019
In experiments which measure subjects’ beliefs, both beliefs about others’ behavior and beliefs about others’ beliefs, are often correlated with a subject’s own choices. Such phenomena have been interpreted as evidence of a causal relationship between beliefs and behavior.
openaire   +2 more sources

A Phase‐Resolved Geometric Deep Learning Framework Maps Structural Determinants of Disease‐Associated Protein Aggregation and Guides Suppressor Design

Advanced Science, EarlyView.
SKALE 2.0 maps disease‐associated protein aggregation as a phase‐resolved structural process, linking mutation‐induced geometric perturbations to nucleation, elongation, and suppressor design. Across neurodegenerative proteins, the framework reveals cryptic aggregation vulnerabilities, separates phase‐concordant and phase‐switching mutations, and ...
Jia Shen Sio, Wei Xuan Wilson Loo, Yan Shan Loo, Wen Xin Tan, Hui Xuan Lim, Huitao Liu, Chen Seng Ng   +6 more
wiley   +1 more source