Results 41 to 50 of about 35,763 (256)
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Global Behavior of a New Rational Nonlinear Higher-Order Difference Equation
Complexity, 2019 Let k be a nonnegative integer and c a real number greater than or equal to 1. We present qualitative global behavior of solutions to a rational nonlinear higher-order difference equation zn+1=(czn+zn-k+c-1znzn-k)/(znzn-k+c), n≥0, with positive initial ...
Wen-Xiu Ma
doaj +1 more source
The Form of the Solutions of System of Rational Difference Equation
Journal of Mathematical Sciences and Modelling, 2018 In this article, we study the form of the solutions of the system of difference equations $x_{n+1}=((y_{n-8})/(1+y_{n-2}x_{n-5}y_{n-8}))$, $y_{n+1}=((x_{n-8})/(\pm1\pm x_{n-2}y_{n-5}x_{n-8}))$, with the initial conditions are real numbers.
E. M. Elsayed, Marwa M. Alzubaidi
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Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Global behavior of a rational difference equation with quadratic term [PDF]
Mathematica Moravica, 2014 In this paper, we determine the forbidden set, introduce an explicit formula for the solutions and discuss the global behavior of all solutions of the difference equation Xn+1 = aXnXn-1 bXn - CXn-2, n = 0, 1, … where a, b, c are positive real numbers and
Abo-Zeid R.
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Dynamical Behavior of a System of Third-Order Rational Difference Equation
Discrete Dynamics in Nature and Society, 2015 This paper deals with the boundedness, persistence, and global asymptotic stability of positive solution for a system of third-order rational difference equations xn+1=A+xn/yn-1yn-2, yn+1=A+yn/xn-1xn-2, n=0,1,…, where A∈(0,∞), x-i∈(0,∞); y-i∈(0,∞), i=0,1,
Qianhong Zhang +2 more
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
On The Recursive Sequence x(n+1)=x(n-20)/[1+x(n-2)x(n-5)x(n-8)x(n-11)x(n-14)x(n-17)]
MANAS: Journal of Engineering, 2019 The behaivour of the solutions of the following system ofdifference equations is examined,x(n+1)=x(n-20)/[1+x(n-2)x(n-5)x(n-8)x(n-11)x(n-14)x(n-17)]where the initial conditions are positive real numbers.The initial conditions of the equation are ...
Burak Oğul, Dağıstan Şimşek
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Behavior of solutions of a second order rational difference equation [PDF]
Mathematica Moravica, 2019 In this paper, we solve the difference equation xn+1 = α xnxn-1 - 1 , n = 0, 1, . . . , where α > 0 and the initial values x-1, x0 are real numbers. We find some invariant sets and discuss the global behavior of the solutions of that equation.
Abo-Zeid Raafat
doaj
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source