Results 41 to 50 of about 6,460,965 (277)

KONSELING DENGAN PENDEKATAN RATIONAL EMOTIVE BEHAVIOR THERAPY UNTUK MENGATASI KEBIASAAN MEROKOK

open access: yesTarbawi, 2018
Smoking is an act of waste and waste on property. The purpose of this study were to described: 1) smoking habits of students before giving Rational Emotive therapy?
Rina Lestari
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Development of the Multidimensional Scale of Irrational Beliefs (MSIB) [PDF]

open access: yes, 2008
The Multidimensional Scale of Irrational Beliefs (MSIB) is a brief and theoretically founded measure of irrational thinking as conceptualized by Albert Ellis in his most recent works on Rational Emotive Behavior Therapy (e.g., Ellis, 2003).
Spörrle, Matthias   +4 more
core   +1 more source

Group Guidance using Rational Emotive Behavior Therapy Approach to Reduce Verbal Bullying

open access: yesPamomong, 2022
Having poor problem solving skills may cause someone to experience verbal bullying. Verbal bullying in adolescents can be manifested into several forms, for instance giving nicknames, reproaches, slander, cruel criticism, insults, gossip, ostracism, and ...
Nur Alfiah   +3 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Rational Emotive Behavior Counseling with Mindfulness Techniques (Ruqyah Meditation) to Increase The Noble Character of Students

open access: yesBisma The Journal of Counseling, 2022
This research was conducted to develop and test the acceptability of Counseling Guidance books with Indonesian culture-based mindfulness techniques (Ruqyah Meditation) to improve the noble character of students in Islamic boarding schools and to ...
Ach. Firman Ilahi   +2 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Rational Emotive Behavior Therapy (REBT) Guidelines To Reduce Student Aggressiveness

open access: yesSCHOULID: Indonesian Journal of School Counseling, 2019
Aggressive behavior is a negative action that is intentionally done by individuals who try to hurt others both physically and verbally. There are many factors that influence adolescent aggression, ridicule, conflict in the family, unfavorable school ...
Dewi Aswira Putri   +3 more
doaj   +1 more source

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