Results 41 to 50 of about 3,933,554 (273)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Influence of Occupational Stress on Work Engagement among Nigerian Library Personnel

Journal An-Nafs: Kajian Penelitian Psikologi, 2022
The study examined occupational stress and job engagement among library personnel at selected Nigerian state and federal universities. A descriptive survey methodology was employed in the study.
Chiedu Eseadi, Charity Neejide Onyishi, Osita Victor Ossai   +2 more
doaj   +1 more source

The Comparison of the Effectiveness of Psychodrama, Reminiscence and Rational-Emotional and Behavioral Treatment on Death Anxiety in the Elderly [PDF]

روانشناسی پیری, 2020
Given the growing number of elderly population, the importance of old age and the problems this age group faces in the society, such as death anxiety (DA), identifying and comparing interventions to improve elderlies’ mental health, treatment and ...
Nayereh Mardi, Mokhtar Arefi, Khodamorad Momeni, Hasan Amiri   +3 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

The Influence of Group Counseling with a Rational Emotive Behavioral Therapy (REBT) Approach on Enhancing Students' Learning Motivation

Jurnal Pamator
A research team at SMP Negeri 17 Medan began observing the desire of ninth-grade students to learn using the Rational Emotive Behavior Therapy (REBT) method. Students from classes IX-A and IX-B, representing a total population of 25, with 8 samples taken
Dinayanti Dinayanti, Nurussakinah Daulay
doaj   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

ADHDCoach—a virtual clinic for parents of children with ADHD: Development and usability study

Digital Health, 2023
Attention-deficit/ hyperactivity disorder (ADHD) is one of the most common mental health problems in childhood. Despite the fact that evidence-based treatments exist, behavioral parent training programs are the gold standard in the care of children with ...
Costina-Ruxandra Păsărelu, Daniel David, Anca Dobrean, Alexandru Noje, Șipoș Roxana, Elena Predescu   +5 more
doaj   +1 more source

Psychological mechanism of acceptance and commitment therapy and rational emotive behavior therapy for treating hoarding: Evidence from randomized controlled trials

Frontiers in Public Health, 2023
Hoarding is a common problem behavior worldwide and is detrimental to the physical and mental health of individuals and groups. Currently, effective interventions for hoarding are cognitive-behavioral therapies, but their post-intervention efficacy is ...
Shuanghu Fang, Dongyan Ding, Ru Zhang, Mingjie Huang   +3 more
doaj   +1 more source