Results 71 to 80 of about 5,856,460 (293)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Shape preserving rational cubic spline for positive and convex data
Egyptian Informatics Journal, 2011 In this paper, the problem of shape preserving C2 rational cubic spline has been proposed. The shapes of the positive and convex data are under discussion of the proposed spline solutions. A C2 rational cubic function with two families of free parameters
Malik Zawwar Hussain +2 more
doaj +1 more source
$D$-resultant for rational functions [PDF]
Proceedings of the American Mathematical Society, 2002 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Yu, JT, Rubio, R, Gutierrez, J
openaire +4 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
, 2012 Rational functions are transformations from words to words that can be defined by string transducers. Rational functions are also captured by deterministic string transducers with lookahead. We show for the first time that the class of rational functions can be learned in the limit with polynomial time and data, when represented by string transducers ...
Boiret, Adrien +2 more
openaire +3 more sources
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
A Fractalization of Rational Trigonometric Functions
Mediterranean Journal of Mathematics, 2020 16 pages, 4 ...
Verma, S., Viswanathan, P.
openaire +2 more sources
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Cauchy type functional equations related to some associative rational functions
Annales Universitatis Paedagogicae Cracoviensis: Studia Mathematica, 2019 L. Losonczi [4] determined local solutions of the generalized Cauchy equation f(F(x, y))= f(x) + f(y) on components of the denition of a given associative rational function F. The class of the associative rational function was described by A. Chéritat [1]
Katarzyna Domańska
doaj
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source