A Universal Protein Ladder for Standardization of Diverse FRET Assays
Translating FRET measurements from in vitro to intracellular environments requires universal benchmarks. We present a modular protein ladder using TPR motifs to harmonize data across diverse platforms. This predictable calibration curve bridges single molecule FRET measurements, with cell based measurements including FLIM‐FRET.
Evelyn R. Smith +5 more
wiley +1 more source
Cefuroxime-induced toxic epidermal necrolysis in a 4-year-old male child: a case report. [PDF]
Khan A +5 more
europepmc +1 more source
Black Hole Quencher‐Enhanced Plasmonic Photothermal Conversion
Researchers have developed a universal method to boost plasmonic photothermal conversion by attaching black hole quencher (BHQ) molecules to matched metal nanostructures. This hybrid approach increases efficiency by roughly threefold, reaching up to 69.1% in the near‐infrared‐II window.
Ruiyuan Zhang +3 more
wiley +1 more source
Expert opinion and clinical practice recommendations using a modified Delphi approach for pediatric acute cough evaluation and management in India. [PDF]
Jindal S +9 more
europepmc +1 more source
Programmable Nanobody‐Targeting Chimeras Enable Intracellular Viral Protein Degradation
Nab‐TAC enables targeted degradation of HBV surface antigen (HBsAg) in vivo. By fusing nanobody‐based recognition domains with programmable proteasome‐recruiting degradation signals, Nab‐TAC reduces HBsAg levels in a hydrodynamic HBV mouse model. ABSTRACT Chronic hepatitis B virus (HBV) infection remains a major global health challenge, largely because
Max Yu‐Chen Pan +11 more
wiley +1 more source
Engineering oriented shape optimization of GHT-Bézier developable surfaces using a meta heuristic approach with CAD/CAM applications. [PDF]
BiBi S +6 more
europepmc +1 more source
Hydrogen‐bonding‐directed assembly enables molecular‐level integration of a covalent organic framework and NiZnCo nanoclusters. The engineered interface couples directional charge transfer, multimetal synergy, and photothermal‐assisted catalysis, providing a versatile strategy for efficient noble‐metal‐free solar hydrogen production.
Ailing Pan +5 more
wiley +1 more source
Steroid Recognition in Adhesion GPCRs: A Structural and Pharmacological Perspective. [PDF]
Fleming B +4 more
europepmc +1 more source
Selective Catalytic Production of Urea: Unravelling the Pairwise Competition on p‐d Alloy Catalysts
Unraveling the complicated competition in urea electrosynthesis, this work investigates asymmetric p‐d alloys. We establish two stage‐specific descriptors, Anchoring Affinity and Coupling Propensity, to elegantly quantify thermodynamic bottlenecks.
Qingchao Fang +6 more
wiley +1 more source
Monomorphic epitheliotropic intestinal T-cell lymphoma presenting as acute small intestinal perforation: a case report and exploratory BCL-2-targeted therapy. [PDF]
He M +7 more
europepmc +1 more source

