Results 41 to 50 of about 3,322 (264)

Analytical Examination of Neo-Mu'tazilite Theories: Insights from the Thought of Muhammad Abed Al-Jabri and Implications for Religious Education [PDF]

Pizhūhish/nāmah-i Mabānī-i Ta̒līm va Tarbiyat.
The present study focuses on Neo-mu'tazila theories with an emphasis on the thoughts of Mohammad Abed Al-Jaberi and its implications for religious education.
Hossein Abdullahzadeh Homirani , Babak Shamshiri, Saeed Rahimian, Mohammad Jafar Mahalati   +3 more
doaj   +1 more source

No more this than that: skeptical impression or Pyrrhonian dogma? [PDF]

SCHOLE, 2017
This is a defense of Pyrrhonian skepticism against the charge that the suspension of judgment based on equipollence is vitiated by the assent given to the equipollence in question.
Necip Fikri Alican
doaj   +1 more source

Trust/distrust judgments and perceptions of climate science: A research note on skeptics’ rationalizations [PDF]

Public Understanding of Science, 2019
Using interviews with residents of Idaho (a rural northwest US state) who identify as skeptical of climate change, we examine how skeptics rationalize their doubts about climate science. Skeptics tend to question the reality and human causes of climate change by (1) raising concerns about incentive structures in science that could bias climatology, (2)
Dilshani Sarathchandra, Kristin Haltinner   +1 more
openaire   +2 more sources

Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome

Advanced Science, EarlyView.
Pharmacological SUMOylation inhibition (SUMOi) counteracts tumor immune evasion by unmasking an immunogenic HLA‐I peptide and neoepitope repertoire. By restoring HLA‐I ligand availability through increased antigen processing and presentation, enhanced proteasomal cleavage, and modulated TAP1 peptide affinity, SUMOi boosts tumor immunogenicity ...
Uta M. Demel, Anna Meurer, Badeel Kh. Q. Zaghla, Bilge Atay, Daniel Steiert, Luca V. Hummel, Konstandina Isaakidis, Chuanbing Zang, Michael Korenkov, Marlon Schielin, Schayan Yousefian, Shima Mecklenbräuker, Marieluise Kirchner, Simon Haas, Antonia Busse, Philipp Mertins, Stefan Müller, Matthias Wirth, Martin G. Klatt, Ulrich Keller   +19 more
wiley   +1 more source

Ligand‐Induced Electronic Response Enables Predictive QM/MM Simulations

Advanced Science, EarlyView.
Quantum mechanics/molecular mechanics (QM/MM) simulations are powerful tools for modeling complex molecular systems; however, their predictability has been constrained by the ambiguous definition of the QM region. An electronically informed protocol is introduced that defines QM regions by quantifying guest‐induced orbital shifts and charge ...
Nichika Ozawa, Nahoko Kuroki, Hirotoshi Mori   +2 more
wiley   +1 more source

Mapping CSC‐Mediated Ovarian Cancer Chemoresistance via CXCR4‐PET to Guide Precision Cisplatin Re‐Sensitization Therapy

Advanced Science, EarlyView.
CXCR4 functions as a potential cancer stem cell‐associated marker linked to chemoresistance in ovarian cancer, and an inhibitor of CXCR4, AMD3100, can enhance the cytotoxic response to cisplatin. Based on these findings, [68Ga]Ga‐Pentixafor positron emission tomography enables selective visualization of CXCR4‐high ovarian cancer, while AMD3100 combined
Lixia Feng, Simei Zhao, Zheng Wei, Wenwen Wang, Feiquan Ying, Lin Huang, Mengna Zhu, Mengqing Chen, Qiang Yang, Si Sun, Dawei Jiang, Lingling Gao, Jing Cai   +12 more
wiley   +1 more source

Abnormal psychology by another name

Discover Psychology
Stigma adds a significant burden for persons with mental illness, and extant research supports multifaceted efforts to reduce that stigma. Stigma reduction is the goal of a recent push to change the name of the college course, Abnormal Psychology, but ...
Timothy K. Daugherty, Mikayla M. Campbell, Blayne D. Stemple, Bradley K. Powers   +3 more
doaj   +1 more source

Bitcoin Unveiled: A Rational Exploration for Skeptical Minds

, 2023
<p>From its inception in 2008 as an idea, Bitcoin has evolved into a functional system by 2009 and found its initial real-world usage in 2010, priced at less than $0.01 per coin. Over time, it has transformed into a globally recognized currency, with each coin valued at over $8,000 and the total market value exceeding $150 billion as of May 2020.
openaire   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Neural Network‐Based Permittivity Engineering of Magnetic Absorbers for Customizable Microwave Absorption

Advanced Science, EarlyView.
A neural network‐enabled permittivity engineering paradigm is introduced, transcending traditional trial‐and‐error design. By decoupling electromagnetic parameters and screening a high‐throughput feature space, an ultrathin (1.0 mm) magnetic absorber is inversely designed, experimentally achieving a superior and customizable 5.1 GHz bandwidth and ...
Chenxi Liu, Jinzhe Li, Sen Li, Zhongqiu Guo, Yao Chen, Tian Li, Renchi Qin, Jiaxu Sun, Yongxi Lu, Fanbin Meng   +9 more
wiley   +1 more source