Results 41 to 50 of about 15,451 (255)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
SN Applied Sciences, 2022 Cooperative automated vehicle software needs to use advanced software engineering design methodologies to manage the complexity of distributed software.
Narsimlu Kemsaram +2 more
doaj +1 more source
Theoretical evaluation of the ability to process on the rational unified process Moprosoftx
Industrial Data, 2010 La determinación de la capacidad de los procesos en empresas que desarrollan software es un tema que ha cobrado interés, pues a través de ellas se las puede califi car en un determinado nivel de capacidad o madurez, según el modelo usado. Además, algunas empresas cuentan con un conjunto de prácticas y metodologías de trabajo establecidas, que en el ...
Canepa Vega, Katia, Dávila, Abraham
openaire +2 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
JSiI (Jurnal Sistem Informasi)In many organizations, including the Institut Teknologi Perusahaan Listrik Negara (ITPLN), letter management and organization is very important. This process is often resource-intensive and time-consuming. With the advancement of information technology,
Filan Firmansyah +2 more
doaj +1 more source
Organizacijų Vadyba: Sisteminiai Tyrimai, 2017 This article is intended to theoretically justify the decision-making process model for the cases, when active participation of investing entities in controlling the activities of an organisation and their results is noticeable.
Bakanauskienė Irena, Baronienė Laura
doaj +1 more source
The UML and the Rational Unified Process [PDF]
IEEE Software, 2020 Dave Bernstein, Grady Booch
openaire +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source