Results 131 to 140 of about 1,523,647 (396)
The Rationality Dialogy Between Economics and Psychology
Economics and psychology take distinct approaches to predicting and formalizing human behavior. Economics focuses on the normative view of rationality, while psychology emphasizes the descriptive nature of rationality.
Jing Qian
doaj +1 more source
Weakest Collective Rationality and the Nash Bargaining Solution [PDF]
We propose a new axiom, Weakest Collective Rationality (WCR) which is weaker than both Weak Pareto Optimality (WPO) in Nash (1950)’s original characterization and Strong Individual Rationality (SIR) in Roth (1977)’s characterization of the Nash ...
Ching-jen Sun, Nejat Anbarci
core
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
How citizens’ experience of democracy can actually pave the way to democratic backsliding
Why do many citizens of Western Europe appear complacent about their societies’ democratic backsliding? This behavior can be at least partly explained by the effect of personal experience on risk perception: a stable democratic past lulls humans into a ...
Ralph Hertwig, Stephan Lewandowsky
doaj +1 more source
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Cobordism invariants of the moduli space of stable pairs
For a quasi-projective scheme M which carries a perfect obstruction theory, we construct the virtual cobordism class of M. If M is projective, we prove that the corresponding Chern numbers of the virtual cobordism class are given by integrals of the ...
Shen, Junliang
core +1 more source
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source

