Results 141 to 150 of about 729,207 (352)

Statins induce monocytic differentiation in acute myeloid leukemia cells through the KLF4/DPYSL2A axis

open access: yesFEBS Open Bio, EarlyView.
Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura   +7 more
wiley   +1 more source

Key role for inhibins in effective T cell activation, migration and Th17 differentiation

open access: yesFEBS Open Bio, EarlyView.
Activins/inhibins modulate immune responses. Here, we show that inhibins can be produced very early after T cell activation and can act in an autocrine way, favoring Th1 versus Th17 differentiation and CCL19/CCL21 mediated migration. Recombinant inhibin A can restore the Th1/Th17 balance, highlighting the role of inhibins as key regulators of T cell ...
Sandra Ortega‐Francisco   +5 more
wiley   +1 more source

Why Rationality May Be a Consequence of Hume's Theory of Choice [PDF]

open access: yes
Facing R. Sugden's criticism of our interpretation, it is shown in this paper that rationality appears as a possible consequence of Hume's theory of choice.
André Lapidus, Marc-Arthur Diaye
core  

Identification of amino acids essential for angulin‐1/3 binding of the tricellular tight junction binder, angubindin‐1

open access: yesFEBS Open Bio, EarlyView.
Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu   +8 more
wiley   +1 more source

Bounded Rationality in the Economics of Organization Present Use and (Some) Future Possibilities [PDF]

open access: yes
The way in which bounded rationality enters contemporary organizational economics theorizing is examined. It is argued that, as it is being used, bounded rationality is neither necessary nor sufficient for producing the results of organizational ...
Nicolai J. Foss
core  

Strengthening Dental Materiovigilance: A Review of International Reporting Frameworks

open access: yesInternational Dental Journal
Dental and medical devices are fundamental to oral healthcare delivery; however, their growing utilization and increasing variety of products due to the material innovation, introduces potential risks of adverse events.
Shalya Anand, Ömer Faruk Sönmez
doaj   +1 more source

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