Results 191 to 200 of about 709,545 (374)

An enzyme‐linked immunosorbent assay (ELISA)‐based activity assay for AMP‐activated protein kinase (AMPK)

open access: yesFEBS Open Bio, EarlyView.
Measuring AMP‐activated protein kinase (AMPK) activity in vitro is crucial for testing AMPK activators or inhibitors with therapeutic potential. Here, we report an enzyme‐linked immunosorbent assay (ELISA)‐based AMPK activity assay with simple steps and high sensitivity, which offers a simple, robust, and cost‐effective alternative to traditional ...
Trezze P. Nguyen, Shangze Lyu, Yang Liu
wiley   +1 more source

Simon's Bounded Rationality. Origins and use in economic theory [PDF]

open access: yes
The paper aims to show how Simon's notion of bounded rationality should be interpreted in the light of its connection with artificial intelligence. This connection points out that bounded rationality is a highly structured concept, and sheds light on ...
Fiori Stefano
core  

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

open access: yesFEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel   +13 more
wiley   +1 more source

Uniformly semi-rational groups [PDF]

open access: yesarXiv
We introduce and study some families of groups whose irreducible characters take values on quadratic extensions of the rationals. We focus mostly on a generalization of inverse semi-rational groups, which we call uniformly semi-rational groups. Moreover, we associate to every finite group two invariants, called rationality and semi-rationality of the ...
arxiv  

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei   +7 more
wiley   +1 more source

Rational conjugacy classes and rational characters for some finite simple groups [PDF]

open access: yesarXiv
If $G$ is a finite group, an irreducible complex-valued character $\chi$ is called rational if $\chi(g)$ is rational for all $g\in G$. Also, a conjugacy class $x^G$ is called rational, if for all irreducible complex-valued character $\chi$, the value $\chi(x^G)$ is rational.
arxiv  

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