Results 61 to 70 of about 2,701,183 (228)

Task Constraints Affect Mapping From Approximate Number System Estimates to Symbolic Numbers

open access: yesFrontiers in Psychology, 2018
The Approximate Number System (ANS) allows individuals to assess nonsymbolic numerical magnitudes (e.g., the number of apples on a tree) without counting.
Dana L. Chesney, Percival G. Matthews
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Complete convergence for arrays of ratios of order statistics

open access: yesOpen Mathematics, 2019
Let {Xn,k, 1 ≤ k ≤ mn, n ≥ 1} be an array of independent random variables from the Pareto distribution. Let Xn(k) be the kth largest order statistic from the nth row of the array and set Rn,in,jn = Xn(jn)/Xn(in) where jn < in. The aim of this paper is to
Miao Yu   +3 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

The Effects of IFRS on Financial Ratios: Early Evidence in Canada [PDF]

open access: yes
This paper provides preliminary evidence of the impact on financial ratios caused by the transition to International Financial Reporting Standards (IFRS) in Canada. The main features of IFRS are explained in the context of a shift from Canadian Generally
François-Éric Racicot   +2 more
core  

Measuring the hotels' performance using profitability ratios [PDF]

open access: yes, 2022
The hospitality industry in Portugal has grown significantly through the year 2019, making a significant contribution to the country's economy. However, with the emergence of the Covid-19 pandemic, this industry was severely damaged and saw its ...
Malheiros, Cátia   +3 more
core   +1 more source

The Role of Albumin-To-Fibrinogen and Fibrinogen-To-Prealbumin Ratios in the Development of Ovarian Carcinoma

open access: yesActa Medica Bulgarica
Ovarian carcinoma (OC) has the highest mortality among gynecological carcinomas in developed countries. Many authors have drawn attention to fibrinogen-to-pre-albumin (FPR) and albumin-to-fibrinogen (AFR) ratios and demonstrated that low AFR values and ...
Racheva V.   +5 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

"Tax ratios in macroeconomics: Do taxes really mater? [PDF]

open access: yes
In various empirical studies so-called tax ratios (tax revenues expressed as a ratio of some aggregate tax base) are employed as approximations for tax burdens.
Bjorn Volkerink   +2 more
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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