Results 1 to 10 of about 2,645 (149)

Mechanisms Underlying the Functional Cooperation Between PPARα and GRα to Attenuate Inflammatory Responses [PDF]

Frontiers in Immunology, 2019
Glucocorticoids (GCs) act via the glucocorticoid receptor (NR3C1, GRα) to combat overshooting responses to infectious stimuli, including lipopolysaccharide (LPS).
Nadia Bougarne, Nadia Bougarne, Nadia Bougarne, Viacheslav Mylka, Viacheslav Mylka, Viacheslav Mylka, Dariusz Ratman, Dariusz Ratman, Dariusz Ratman, Ilse M. Beck, Jonathan Thommis, Jonathan Thommis, Jonathan Thommis, Lode De Cauwer, Lode De Cauwer, Lode De Cauwer, Jan Tavernier, Jan Tavernier, Jan Tavernier, Bart Staels, Claude Libert, Claude Libert, Karolien De Bosscher, Karolien De Bosscher, Karolien De Bosscher   +24 more
doaj   +5 more sources

The ArcAB two-component system is associated with the susceptibility of Aggregatibacter actinomycetemcomitans to superoxide and hydrogen peroxide [PDF]

mSphere
Aggregatibacter actinomycetemcomitans is a Gram-negative facultative anaerobe and is associated with periodontal disease. This bacterium is exposed to environmental stresses, such as osmotic pressure, temperature shifts, pH shifts, and antimicrobial ...
Mohammad Farid Ratman, Yuichi Oogai, Airi Matsumoto, Masanobu Nakata   +3 more
doaj   +3 more sources

Crosstalk interactions between transcription factors ERRα and PPARα assist PPARα-mediated gene expression [PDF]

Molecular Metabolism
Objective: The peroxisome proliferator-activated receptor α (PPARα) is a transcription factor driving target genes involved in fatty acid β-oxidation. To what extent various PPARα interacting proteins may assist its function as a transcription factor is ...
Sofie J. Desmet, Jonathan Thommis, Tineke Vanderhaeghen, Edmee M.F. Vandenboorn, Dorien Clarisse, Yunkun Li, Steven Timmermans, Daria Fijalkowska, Dariusz Ratman, Evelien Van Hamme, Lode De Cauwer, Bart Staels, Luc Brunsveld, Frank Peelman, Claude Libert, Jan Tavernier, Karolien De Bosscher   +16 more
doaj   +3 more sources

Foam Behaviour of An Aqueous Solution of Piperazine- N-Methyldiethanolamine (MDEA) Blend as A Function of The Type of Impurities and Concentrations [PDF]

International Journal of Science and Engineering, 2010
This study focuses on the effect of impurities in the natural gas stream on the characteristic of foam behaviour in the blended piperazine and MDEA solution.
Iwan Ratman, Tutuk Djoko Kusworo, Ahmad Fauzi Ismail   +2 more
doaj   +3 more sources

Interleukin-17 receptor A (IL-17RA) as a central regulator of the protective immune response against Giardia [PDF]

Scientific Reports, 2017
The protozoan parasite Giardia is a highly prevalent intestinal pathogen with a wide host range. Data obtained in mice, cattle and humans revealed the importance of IL-17A in the development of a protective immune response against Giardia.
Oonagh Paerewijck, Brecht Maertens, Leentje Dreesen, Frederik Van Meulder, Iris Peelaers, Dariusz Ratman, Robert W. Li, Erik Lubberts, Karolien De Bosscher, Peter Geldhof   +9 more
doaj   +2 more sources

Comparison of distribution and frequency of impacted teeth before and during COVID-19 pandemic in dental hospital: a descriptive study

Padjadjaran Journal of Dentistry, 2023
Introduction: The occurrence of the COVID-19 pandemic may affect the prevalence of patients with complaints of impacted teeth in dental hospital Faculty of Dentistry University of Indonesia (FKG UI), and there is no recent research on the distribution ...
Haura Syafin, Muhammad Ramaditto Reksoprodjo, Vera Julia, Maudina Dwi Heriasti, Dwi Ariawan, Lilies Dwi Sulistyani, Yudy Ardilla Utomo, Muhammad Farid Ratman   +7 more
doaj   +2 more sources

Compound A influences gene regulation of the Dexamethasone-activated glucocorticoid receptor by alternative cofactor recruitment [PDF]

Scientific Reports, 2017
The glucocorticoid receptor (GR) is a transcription factor of which the underlying gene regulatory mechanisms are complex and incompletely understood. The non-steroidal anti-inflammatory Compound A (CpdA), a selective GR modulating compound in various ...
S. J. Desmet, N. Bougarne, L. Van Moortel, L. De Cauwer, J. Thommis, M. Vuylsteke, D. Ratman, R. Houtman, J. Tavernier, K. De Bosscher   +9 more
doaj   +2 more sources

Chromatin recruitment of activated AMPK drives fasting response genes co-controlled by GR and PPARα. [PDF]

Nucleic Acids Res, 2016
Adaptation to fasting involves both Glucocorticoid Receptor (GRα) and Peroxisome Proliferator-Activated Receptor α (PPARα) activation. Given both receptors can physically interact we investigated the possibility of a genome-wide cross-talk between ...
Ratman D, Mylka V, Bougarne N, Pawlak M, Caron S, Hennuyer N, Paumelle R, De Cauwer L, Thommis J, Rider MH, Libert C, Lievens S, Tavernier J, Staels B, De Bosscher K.   +14 more
europepmc   +2 more sources

What Made the Ratman Sick? [PDF]

, 2005
Article
Cartwright, Nancy
openaire   +2 more sources

Mechanisms of unprimed and dexamethasone-primed nonviral gene delivery to human mesenchymal stem cells. [PDF]

Biotechnol Bioeng, 2019
Human mesenchymal stem cells (hMSCs) are under intense study for applications of cell and gene therapeutics because of their unique immunomodulatory and regenerative properties. Safe and efficient genetic modification of hMSCs could increase their clinical potential by allowing functional expression of therapeutic transgenes or control over behavior ...
Hamann A, Broad K, Nguyen A, Pannier AK.
europepmc   +2 more sources