Results 1 to 10 of about 137 (81)

The ArcAB two-component system is associated with the susceptibility of Aggregatibacter actinomycetemcomitans to superoxide and hydrogen peroxide [PDF]

mSphere
Aggregatibacter actinomycetemcomitans is a Gram-negative facultative anaerobe and is associated with periodontal disease. This bacterium is exposed to environmental stresses, such as osmotic pressure, temperature shifts, pH shifts, and antimicrobial ...
Mohammad Farid Ratman, Yuichi Oogai, Airi Matsumoto, Masanobu Nakata   +3 more
doaj   +2 more sources

Mechanisms Underlying the Functional Cooperation Between PPARα and GRα to Attenuate Inflammatory Responses [PDF]

Frontiers in Immunology, 2019
Glucocorticoids (GCs) act via the glucocorticoid receptor (NR3C1, GRα) to combat overshooting responses to infectious stimuli, including lipopolysaccharide (LPS).
Nadia Bougarne, Nadia Bougarne, Nadia Bougarne, Viacheslav Mylka, Viacheslav Mylka, Viacheslav Mylka, Dariusz Ratman, Dariusz Ratman, Dariusz Ratman, Ilse M. Beck, Jonathan Thommis, Jonathan Thommis, Jonathan Thommis, Lode De Cauwer, Lode De Cauwer, Lode De Cauwer, Jan Tavernier, Jan Tavernier, Jan Tavernier, Bart Staels, Claude Libert, Claude Libert, Karolien De Bosscher, Karolien De Bosscher, Karolien De Bosscher   +24 more
doaj   +2 more sources

Astrocyte Bioenergetic Remodeling as a Central Trait of Disrupted Glucocorticoid Signaling: Mechanisms and Implications for Stress Vulnerability. [PDF]

J Neurochem
Low/brief glucocorticoid (GC) elevations can enhance mitochondrial output (↑ oxygen consumption rate, OCR; ↑ mitochondrial membrane potential, ΔΨm) and Ca2+ buffering, in part via glucocorticoid receptor (GR) trafficking to mitochondria in complexes with Bcl2 and Bag1.
Hanus P, Frydecka D, Ślęzak M.
europepmc   +2 more sources

Outcomes of surgical, medication and combination therapies for cherubism: a systematic review and qualitative analysis [PDF]

Frontiers in Oral Health
BackgroundCherubism is a rare genetic fibro-osseous disorder characterized by symmetrical expansion of the maxilla and mandible. The lesions usually progress during childhood, stabilize around puberty, and regress in adulthood.
Vera Julia, Lilies Dwi Sulistyani, Diwiya Aryyaguna, Revini Nuita, Elizabeth Shinta Maharani, Jovian Purnomo, Dwi Ariawan, Muhammad Adhitya Latief, Yudy Ardilla Utomo, Mohammad Farid Ratman, Norifumi Nakamura   +10 more
doaj   +2 more sources

Crosstalk interactions between transcription factors ERRα and PPARα assist PPARα-mediated gene expression [PDF]

Molecular Metabolism
Objective: The peroxisome proliferator-activated receptor α (PPARα) is a transcription factor driving target genes involved in fatty acid β-oxidation. To what extent various PPARα interacting proteins may assist its function as a transcription factor is ...
Sofie J. Desmet, Jonathan Thommis, Tineke Vanderhaeghen, Edmee M.F. Vandenboorn, Dorien Clarisse, Yunkun Li, Steven Timmermans, Daria Fijalkowska, Dariusz Ratman, Evelien Van Hamme, Lode De Cauwer, Bart Staels, Luc Brunsveld, Frank Peelman, Claude Libert, Jan Tavernier, Karolien De Bosscher   +16 more
doaj   +2 more sources

Interleukin-17 receptor A (IL-17RA) as a central regulator of the protective immune response against Giardia [PDF]

Scientific Reports, 2017
The protozoan parasite Giardia is a highly prevalent intestinal pathogen with a wide host range. Data obtained in mice, cattle and humans revealed the importance of IL-17A in the development of a protective immune response against Giardia.
Oonagh Paerewijck, Brecht Maertens, Leentje Dreesen, Frederik Van Meulder, Iris Peelaers, Dariusz Ratman, Robert W. Li, Erik Lubberts, Karolien De Bosscher, Peter Geldhof   +9 more
doaj   +2 more sources

Compound A influences gene regulation of the Dexamethasone-activated glucocorticoid receptor by alternative cofactor recruitment [PDF]

Scientific Reports, 2017
The glucocorticoid receptor (GR) is a transcription factor of which the underlying gene regulatory mechanisms are complex and incompletely understood. The non-steroidal anti-inflammatory Compound A (CpdA), a selective GR modulating compound in various ...
S. J. Desmet, N. Bougarne, L. Van Moortel, L. De Cauwer, J. Thommis, M. Vuylsteke, D. Ratman, R. Houtman, J. Tavernier, K. De Bosscher   +9 more
doaj   +2 more sources

Pharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells. [PDF]

PLoS ONE, 2014
Withaferin A (WA) isolated from Withania somnifera (Ashwagandha) has recently become an attractive phytochemical under investigation in various preclinical studies for treatment of different cancer types. In the present study, a comparative pathway-based
Katarzyna Szarc vel Szic, Ken Op de Beeck, Dariusz Ratman, An Wouters, Ilse M Beck, Ken Declerck, Karen Heyninck, Erik Fransen, Marc Bracke, Karolien De Bosscher, Filip Lardon, Guy Van Camp, Wim Vanden Berghe   +12 more
doaj   +2 more sources

Stability of integrated polygenic and clinical coronary artery disease risk prediction [PDF]

American Journal of Preventive Cardiology
Dariusz Ratman, Robert Maier, Akash Kumar, Matthew Rabinowitz, Kate Im, Akl C Fahed   +5 more
doaj   +2 more sources

Pengembangan E-Modul Serli Berbasis Android Materi Magnet bagi Siswa Sekolah Dasar

Scaffolding: Jurnal Pendidikan Islam dan Multikulturalisme, 2022
This research is based on the lack of learning media that can help students during Distance Learning. Learning Media developed in this study can be used and accessed anywhere and anytime to help students understand the material being taught.
Enny Rahayu, Azizah Azizah, Ratman Ratman, Iga Risma, Melyani Sari Sitepu   +4 more
doaj   +1 more source