Results 131 to 140 of about 8,257 (145)

Optimized rat models better mimic patients with irinotecan-induced severe diarrhea. [PDF]

open access: yesToxicol Mech Methods
Zheng Z   +8 more
europepmc   +1 more source

Bile Acid Profile Differs Between Brain Regions in Rodents and Is Disrupted in a Rodent Model of Alzheimer's Disease. [PDF]

open access: yesCompr Physiol
Reuter MA   +11 more
europepmc   +1 more source

Antagonizing Activin A/p15INK4b Signaling as Therapeutic Strategy for Liver Disease. [PDF]

open access: yesCells
Mekala S   +7 more
europepmc   +1 more source

Rifaximin Attenuates Liver Fibrosis and Hepatocarcinogenesis in a Rat MASH Model by Suppressing the Gut-Liver Axis and Epiregulin-IL-8-Associated Angiogenesis. [PDF]

open access: yesInt J Mol Sci
Nishimura N   +12 more
europepmc   +1 more source
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Efficient collection and cryopreservation of embryos in F344 strain inbred rats

Cryobiology, 2013
In rats, it is now possible to produce genetically engineered strains, not only as transgenic animals but also using gene knockout techniques. Reproductive technologies have been used as indispensable tools to produce and maintain these novel valuable strains.
Takehito Kaneko, Hiroaki Taketsuru
openaire   +2 more sources

The LEXF: A new set of rat recombinant inbred strains between LE/Stm and F344

Mammalian Genome, 1997
A new set of rat RI strains consisting of 11 independent strains and 13 of their substrains was established by inbreeding F2 rats between F344/DuCrj and LE/Stm. The strain distribution pattern was examined for 66 microsatellite loci, 8 biochemical genetic markers, 2 histocompatibility loci, and 2 coat color genes.
Yoshibumi Matsushima   +6 more
openaire   +3 more sources

Comparison of energy balance in two inbred strains of rats: Fischer F344 prone to obesity and Lou rats resistant to obesity

Physiology & Behavior, 2006
This study aimed to compare energy balance, metabolic profiles and body composition between two inbred strains of rats (F344 and Lou) submitted to a self-selecting macronutrient. During the 3 weeks of experiment, the two strains did not differ significantly for their total energy intake; males: F344 = 5875.4 +/- 171.4 kJ, Lou = 5619.2 +/- 349.4 kJ; and
Abdoulaye, Diane   +6 more
openaire   +5 more sources

Cocaine self-administration and locomotor activity are altered in Lewis and F344 inbred rats by RTI 336, a 3-phenyltropane analog that binds to the dopamine transporter

Brain Research, 2005
Lewis and Fischer 344 (F344) rats differ in responses to cocaine and characteristics of the mesolimbic dopamine system. Compared to F344 rats, Lewis rats have lower D2 receptor and dopamine transporter (DAT) levels in nucleus accumbens (NAc). We showed previously that altering D1 and D2 receptor levels pharmacologically had strain-dependent effects on ...
Xiang Yang Zhang   +3 more
openaire   +2 more sources

Genetic and Cellular Factors in the Immune Response. III. The Cellular Response to Poly(Glu52Lys33Tyr15) in the Highly Responding ACI and Poorly Responding F344 Strains of Inbred Rats

The Journal of Immunology, 1971
Abstract The antibody response in the inbred rat is controlled by at least two autosomal genes; in addition, there is a sex influence which may include both additional genetic factors and environmental influences (1–3). We postulate that one of the major genes controlling the antibody response influences the size of the cell population ...
Thomas J Gill   +3 more
openaire   +1 more source

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