Optimized rat models better mimic patients with irinotecan-induced severe diarrhea. [PDF]
Zheng Z+8 more
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Bile Acid Profile Differs Between Brain Regions in Rodents and Is Disrupted in a Rodent Model of Alzheimer's Disease. [PDF]
Reuter MA+11 more
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Anterior-interrupted and posterior-continuous suture technique improved the success rate of kidney transplantation model in rats. [PDF]
Lu LT, Zou XF, Han SQ.
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Antagonizing Activin A/p15INK4b Signaling as Therapeutic Strategy for Liver Disease. [PDF]
Mekala S+7 more
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Rifaximin Attenuates Liver Fibrosis and Hepatocarcinogenesis in a Rat MASH Model by Suppressing the Gut-Liver Axis and Epiregulin-IL-8-Associated Angiogenesis. [PDF]
Nishimura N+12 more
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Efficient collection and cryopreservation of embryos in F344 strain inbred rats
Cryobiology, 2013In rats, it is now possible to produce genetically engineered strains, not only as transgenic animals but also using gene knockout techniques. Reproductive technologies have been used as indispensable tools to produce and maintain these novel valuable strains.
Takehito Kaneko, Hiroaki Taketsuru
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The LEXF: A new set of rat recombinant inbred strains between LE/Stm and F344
Mammalian Genome, 1997A new set of rat RI strains consisting of 11 independent strains and 13 of their substrains was established by inbreeding F2 rats between F344/DuCrj and LE/Stm. The strain distribution pattern was examined for 66 microsatellite loci, 8 biochemical genetic markers, 2 histocompatibility loci, and 2 coat color genes.
Yoshibumi Matsushima+6 more
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This study aimed to compare energy balance, metabolic profiles and body composition between two inbred strains of rats (F344 and Lou) submitted to a self-selecting macronutrient. During the 3 weeks of experiment, the two strains did not differ significantly for their total energy intake; males: F344 = 5875.4 +/- 171.4 kJ, Lou = 5619.2 +/- 349.4 kJ; and
Abdoulaye, Diane+6 more
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Lewis and Fischer 344 (F344) rats differ in responses to cocaine and characteristics of the mesolimbic dopamine system. Compared to F344 rats, Lewis rats have lower D2 receptor and dopamine transporter (DAT) levels in nucleus accumbens (NAc). We showed previously that altering D1 and D2 receptor levels pharmacologically had strain-dependent effects on ...
Xiang Yang Zhang+3 more
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Abstract The antibody response in the inbred rat is controlled by at least two autosomal genes; in addition, there is a sex influence which may include both additional genetic factors and environmental influences (1–3). We postulate that one of the major genes controlling the antibody response influences the size of the cell population ...
Thomas J Gill+3 more
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