, 2015 Previous work from our laboratories has shown that juvenile Fischer 344 (F344) rats are less playful than other strains and also appear to be compromised in dopamine (DA) functioning.
Akopian, Garnik +5 more
core +1 more source
Evidence of emerging transcriptome mediators of Alzheimer's disease in canine cognitive dysfunction
Brain Pathology, Volume 36, Issue 3, May 2026.Canine cognitive dysfunction (CCD) may be a promising model of Alzheimer's disease (AD). To assess AD‐related molecular signatures in CCD, we generated transcriptome data on dog cortex and plasma extracellular vesicles (EVs). CCD‐related transcriptome changes were similar to those in aging/AD humans and were detectable in EVs from the same animals ...
Shelby C. Osburn +7 more
wiley +1 more source
Evolutionary Applications, Volume 19, Issue 5, May 2026.ABSTRACT The black soldier fly (BSF; Hermetia illucens) is rapidly emerging as a model for evolutionary biology and insect biotechnology. Although larval biology has been extensively characterised, the reproductive biology of adults remains comparatively understudied.
Noah B. Lemke, Nalini Puniamoorthy
wiley +1 more source
Gamma‐irradiated Newcastle disease virus: an alternative inactivated oncolytic virotherapy
Immunology &Cell Biology, Volume 104, Issue 5, Page 473-484, May‐June 2026.To overcome biological risks associated with using live NDV as an oncolytic therapy, we developed gamma‐NDV as a safer alternative. Using a murine model for skin cancer, we show that intratumor administration of gamma‐NDV outperformed live‐NDV in terms of reducing tumor growth and improving overall animal survival. Abstract Newcastle disease virus (NDV)
Eve V Kennedy +10 more
wiley +1 more source
New Phytologist, Volume 250, Issue 4, Page 2516-2534, May 2026.Summary Acclimation enables plants to adjust to immediate environmental fluctuations and is therefore key to the resilience of plant disease resistance in a time of climate change. Here, we report on the acclimation of Arabidopsis thaliana quantitative immune responses against the fungal pathogen Sclerotinia sclerotiorum to daily environmental ...
Marie Didelon +6 more
wiley +1 more source
Assignment of the Human and Mouse Prion Protein Genes to Homologous Chromosomes [PDF]
, 1986 Purified preparations of scrapie prions contain one major macromolecule, designated prion protein (PrP). Genes encoding PrP are found in normal animals and humans but not within the infectious particles.
Blatt, Cila +13 more
core
Differences on the Natural Course of Chronic Kidney Disease Progression, Induced by 5/6 Renal Ablation Model in Three Different Rat Stains: Wistar, Lewis, and Fischer 344. [PDF]
Life (Basel)Jesus S +7 more
europepmc +1 more source
Virus-Specific T-Cell Sensitization. Requirements for vaccinia virus specific T cell sensitization in vivo. [PDF]
, 1977 Ertl, Hildegund +2 more
core +1 more source
Shortcoming of the Mouse Model of Postoperative Ileus: Small Intestinal Lengths Have Similar Variations in In- and Outbred Mice and Cannot Be Predicted by Allometric Parameters. [PDF]
Biomedicinesvon Stumberg M +3 more
europepmc +1 more source
Induction of mammary neoplasms in the SPrague-Dawley rat by 430 keV neutrons and X-rays [PDF]
, 1980 Chmelevsky, D. +2 more
core +1 more source