Positional identification of variants of Adamts16 linked to inherited hypertension [PDF]
A previously reported blood pressure (BP) quantitative trait locus on rat Chromosome 1 was isolated in a short congenic segment spanning 804.6 kb. The 804.6 kb region contained only two genes, LOC306664 and LOC306665.
Achinike, Ovokeraye H. +25 more
core
Creation of a Computational Pipeline to Extract Genes from Quantitative Trait Loci for Diabetes and Obesity [PDF]
Type 2 Diabetes is a disease of relative insulin deficiency resulting from a combination of insulin resistance and decreased beta-cell function. Over the past several years, over 60 genes have been identified for Type 2 Diabetes in human genome-wide ...
Fox, Joseph
core +1 more source
Nociceptin attenuates the escalation of oxycodone self-administration by normalizing CeA-GABA transmission in highly addicted rats. [PDF]
Approximately 25% of patients who are prescribed opioids for chronic pain misuse them, and 5 to 10% develop an opioid use disorder. Although the neurobiological target of opioids is well known, the molecular mechanisms that are responsible for the ...
Carrette, Lieselot LG +7 more
core
Development of the metabolic syndrome is detennined by a complex interaction of environmental and genetic factors and as with other complex human traits, disease gene identification is problematic due to a lack of statistical power and genetic ...
Maciver, Fiona, Maciver, Fiona
core
Effects of nicotine on depressive-like behavior and hippocampal volume of female WKY rats.
Y. Tizabi +6 more
semanticscholar +1 more source
Xanthine oxidoreductase in essential hypertension and metabolic syndrome : Experimental studies on rodent models [PDF]
Hypertension, obesity, dyslipidemia and dysglycemia constitute metabolic syndrome, a major public health concern, which is associated with cardiovascular mortality.
Laakso, Juha
core
New target regions for human hypertension via comparative genomics [PDF]
Cowley Jr., A.W. (Allen) +9 more
core +1 more source
Bacterial Extracellular Vesicles Mediate Microbiota-Host Communication to Regulate Blood Pressure in Male Rats. [PDF]
Shi H +8 more
europepmc +1 more source
Disparate Mechanical and Functional Properties of Spontaneously Hypertensive Rat and Spontaneously Hypertensive Heart Failure Rat Penetrating Arterioles. [PDF]
Acosta C, Anderson HD, Anderson CM.
europepmc +1 more source

