On the importance of including both sexes in animal studies – insights from home‐cage monitoring
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater +12 more
wiley +1 more source
How to explore a new environment: exploratory tactics of the black rat (Rattus rattus). [PDF]
Štolhoferová I +4 more
europepmc +1 more source
The Role of Ferroptosis Induced by Iron Overload in Osteoblast and Osteoclast Function
ABSTRACT Iron overload disrupts bone homeostasis by suppressing osteoblast survival and mineralization, while promoting osteoclastogenesis. As a programmed cell death driven by iron‐dependent lipid peroxidation and glutathione peroxidase 4 (GPX4) downregulation. This study investigated the role of ferroptosis in bone cells under iron overload. Exposure
Supagarn Sooksawanwit +9 more
wiley +1 more source
Microsporidia in Rodents-<i>Mus musculus</i>, <i>Rattus norvegicus,</i> and <i>Rattus rattus</i>-A Public Health Concern in the Canary Islands, Spain. [PDF]
Llorens-Berzosa S +12 more
europepmc +1 more source
ABSTRACT Objective To evaluate the effects of antimicrobial photodynamic therapy (aPDT), systemic pharmacological therapy, and their combination on irradiated mandibular post‐extraction bone repair relevant to osteoradionecrosis (ORN) development in a rat model. Methods Twenty‐six male Wistar rats were initially randomized into five experimental groups:
Larissa Lopes Fonseca +9 more
wiley +1 more source
Hypoglycemic effect of the aqueous extract from <i>Acalypha argomuelleri</i> Briq. (Euphorbiaceae) 'Sweet stick' leaves in <i>Rattus rattus</i> var. <i>albinus</i>. [PDF]
Morales Ramos JG +7 more
europepmc +1 more source
Fluoride as a Modifier of Metallome Homeostasis: A Systematic Review of Animal Studies
ABSTRACT Fluoride is widely used for caries prevention due to its effects on mineralized tissues, yet its potential role as a modifier of systemic metal homeostasis remains insufficiently explored. This systematic review synthesizes preclinical evidence on the association between fluoride exposure and changes in metal and semi‐metal concentrations ...
Natalia Macedo‐Ribeiro +8 more
wiley +1 more source
Dynamic movement patterns of commensal rodents Mastomys natalensis and Rattus rattus: determining differential habitat use using Rhodamine B. [PDF]
Mkomwa H +8 more
europepmc +1 more source

