Results 31 to 40 of about 619,831 (250)

Pathological Copper Overload Reprograms SOD1 Activation via COMMD1 to Promote Senescence and Fibrosis

Advanced Science, EarlyView.
This study uncovers a previously unrecognized copper‐COMMD1‐SOD1 regulatory axis, revealing that pathological copper overload paradoxically suppresses SOD1 activity by promoting COMMD1‐dependent disruption of SOD1 homodimerization. These findings redefine the regulatory role of copper in SOD1 biology and provide novel mechanistic insight into the ...
Yuqing Liu, Jing Liu, Wenqian Zhou, Yangyang Niu, Yan Zheng, Yiguo Liu, Yingying Zhang, Chen Yu   +7 more
wiley   +1 more source

Detection of rat hepatitis E virus in wild Norway rats (Rattus norvegicus) and Black rats (Rattus rattus) from 11 European countries [PDF]

, 2017
International audienceRat hepatitis E virus (HEV) is genetically only distantly related to hepeviruses found in other mammalian reservoirs and in humans.
Ann-Charlotte Heiberg, Groschup, Martin H., Dovas, C., Sebastian Guenther, Zanet, Stefania, Gerald Heckel, Tsakmakidis, Joannis, René Ryll, Pépin, M., Spahr, C., Ruiz-Fons, Francisco, Ulrich, Rainer, Heuser, Elisa, Michel Pépin, Bajomi, D., Heckel, Gerald, Chrysostomos Dovas, Christian Imholt, Rainer G. Ulrich, Spahr, Carina, Lang, J., Zumpe, Maxi, Johne, Reimar, Tsakmakidis, Ioannis, Knap, Nataša, Ruiz-Fonscisco, Francisco, Gabi Müller, Wolf, Sandro, Paul Dremsek, Ansorge, Hermann, Dovas, Chrysostomos, Reimar Johne, Ulrich, Rainer, G., Freise, Jona, Bajomi, Daniel, Pikula, Jiri, Nataša Knap, Ansorge, H., Elisa Heuser, Freise, J., Imholt, Christian, Heiberg, Ann-Charlotte, Guenther, Sebastian, Ryll, René, Pépin, Michel, Ulrich, Rainer,, Kristof Baert, Jiri Pikula, Hermann Ansorge, Schlegel, Matthias, Carina Spahr, Sandro Wolf, Ιoannis Tsakmakidis, Bernstein, Samuel, Samuel Bernstein, Johannes Lang, Dremsek, Paul, Ulrich, Rainer G., Maxi Zumpe, Stefania Zanet, Schlegel, Mathias, Müller, Gabi, Daniel Bajomi, Baert, Kristof, Jona Freise, Martin H. Groschup, Wolf, S., Francisco Ruiz-Fons, Mathias Schlegel, Lang, Johannes, Müller, G.   +70 more
core   +1 more source

Rhipicephalus sanguineus sensu lato(Ixodidae) in synantropic rodents in Rio Grande do Sul, Brazil

Revista Brasileira de Parasitologia Veterinária
Rhipicephalus sanguineus, the brown dog tick, is responsible for maintaining and transmitting various pathogens, both in animals and human beings, and it is of great sanitary importance.
Kathleen Tavares Winkel, Paulo Bretanha Ribeiro, Lidiane Oliveira Antunes, Marcial Corrêa Cárcamo, Élvia Elena Silveira Vianna   +4 more
doaj   +1 more source

The tick Ixodes granulatus infests Rattus rattus populating a small island offshore of Singapore

Parasite, 2006
The ixodid tick Ixodes granulosus Supino 1897 was found infesting Rattus rattus in Semakau island, one of the small offshore islands fringing Singapore to the south. None of the examined R.
Paperna I.
doaj   +1 more source

Identificación de helmintos en Didelphis marsupialis (Didelphidae) y Rattus rattus (Muridae) en el área metropolitana de Bucaramanga, Colombia

Actualidades Biológicas, 2021
Objetivo. Evaluar la presencia de helmintos en Didelphis marsupialis y Rattus rattus en zonas de invasión del Caracol Gigante Africano Achatina fulica en el área metropolitana de Bucaramanga, Santander. Metodología.
Antonio Betancourt-Echeverri, Andrés Pereira-Patiño, Wendy Quintero-García, Paola López-Rueda, Nelson Uribe-Delgado   +4 more
doaj   +1 more source

RNA Promotes Synapsin Condensates That Organize Synaptic Vesicles in Live Neurons and Enable Localized Translation in Reconstituted System

Advanced Science, EarlyView.
Condensates at synapses organize synaptic vesicles (SVs) and are crucial for efficient neurotransmitter release, yet how RNA contributes to this mesoscale architecture remains poorly understood. Here we uncover that RNA modulates synapsin–driven condensates.
Branislava Rankovic, Zachary M. Geisterfer, Akshita Chhabra, Vladimir M. Jovanovic, Ian Seim, Christian Hoffmann, Antonela Condric, Gerard Aguilar Pérez, Rinse de Boer, Lars T. Hofstede, Jingao Sun, Kiara Freitag, Katja Nowick, Marina Jendrach, Frank L. Heppner, Vladimir Despic, Michaela Müller‐McNicoll, Stephan Sigrist, Geert van den Bogaart, Sofiia Reshetniak, Amy S. Gladfelter, Dragomir Milovanovic   +21 more
wiley   +1 more source

A new nuclear marker, the “VKORC1 gene exon 3 region”, for the identification of Anatolian Rattus spp.

BMC Zoology
In this study, exons 1, 2, and 3 of the vitamin K epoxide reductase complex subunit 1 (VKORC1) gene, which has been used to indicate anticoagulant rodenticide resistance, were analyzed to investigate whether it is an effective marker for the ...
Derya Çetintürk, Mustafa Türker Duman, Nuri Yiğit   +2 more
doaj   +1 more source

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

Advanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang, Zitong Huang, Yu Tao, Yunmei Zhang, Yufang Sun, Dongsheng Jiang, Weiwei Lu, Fuhai Ji, Gang Chen, Min Xu, Yuan Zhang, Jin Tao   +11 more
wiley   +1 more source

The biology and behaviour of a free-living population of black rats (Rattus rattus) [PDF]

, 2010
A population of wild Rattus rattus living in the roofs of the laboratory buildings was studied by supplying food every evening and watching the behaviour of the animals at the feeding place. Some observations were also made on caged animals.
Ewer, Rosalie F.
core  

Patterns of helminth infections in Rattus rattus and Mus musculus from two Mayan communities in Mexico

, 2019
The black rat Rattus rattus and the house mouse Mus musculus are two commensal rodent species that harbour and shed zoonotic pathogens, including helminths.
Panti May, Jesús Alonso, Robles, Maria del Rosario, Hernández Betancourt, S. F., Palomo Arjona, E. E., Machain Williams, Carlos, Barrientos Medina, R. C., Gurubel González, Y. M., Digiani, Maria Celina   +7 more
core   +1 more source