Results 31 to 40 of about 765,254 (255)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Some technical aspects of the rheological properties of high concentration fine suspensions to avoid environmental disasters

Journal of Environmental Engineering and Landscape Management, 2015
The behavior of slurries and suspensions made by mixing solid particles and liquids is very important for various industrial applications. The latest accidental failure events at tailings facilities (Kolontár, Baia Mare) have focused public interest into
József Faitli, Imre Gombkötő
doaj   +1 more source

Study on the Mineralogical Characteristics of 12 Copper Concentrates by X-ray Fluorescence Spectrometry, X-ray Powder Diffraction and Polarization Microscope

Yankuang ceshi, 2021
BACKGROUND China is the largest importer of copper concentrate in the world. Studying the mineralogical characteristics of copper concentrates imported from different origins can be used to support the origin analysis and solid waste identification of ...
MIN Hong, LIU Qian, ZHANG Jin-yang, ZHOU Hai-ming, YAN De-tian, XING Yan-jun, LI Chen, LIU Shu   +7 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

COMBINED UTILIZATION OF RED MUD AND MECHANICALLY ACTIVATED FLY ASH IN GEOPOLYMERS

Rudarsko-geološko-naftni Zbornik, 2019
This paper focuses on the investigation of the co-utilization of two major industrial waste materials, power station fly ash and red mud. Experimental studies were carried out to establish the correlation between the physical properties of a geopolymer ...
Gábor Mucsi, Roland Szabó, Ádám Rácz, Ferenc Kristály, Sanjay Kumar   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Effects of Oxathiapiprolin on the Structure, Diversity and Function of Soil Fungal Community

Toxics, 2022
Pesticides can affect non-target microorganisms in the soil and are directly related to soil microecological health and environmental safety. Oxathiapiprolin is a piperidinyl thiazole isoxazoline fungicide that shows excellent control effect against ...
Yuxuan Chen, Fengwen Zhang, Bin Huang, Jie Wang, Haixia Huang, Zhanfeng Song, Shiying Nong, Chongjun Huang, Jianyu Wei, Haijiang Jia   +9 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Analysis of Operational Control Data and Development of a Predictive Model of the Content of the Target Component in Melting Products

Eng
The relevance of this research is due to the need to stabilize the composition of the melting products of copper–nickel sulfide raw materials. Statistical methods of analyzing the historical data of the real technological object and the correlation ...
Natalia Vasilyeva, Ivan Pavlyuk
doaj   +1 more source