Results 31 to 40 of about 765,969 (310)
BACKGROUND China is the largest importer of copper concentrate in the world. Studying the mineralogical characteristics of copper concentrates imported from different origins can be used to support the origin analysis and solid waste identification of ...
MIN Hong +7 more
doaj +1 more source
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
The behavior of slurries and suspensions made by mixing solid particles and liquids is very important for various industrial applications. The latest accidental failure events at tailings facilities (Kolontár, Baia Mare) have focused public interest into
József Faitli, Imre Gombkötő
doaj +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
The relevance of this research is due to the need to stabilize the composition of the melting products of copper–nickel sulfide raw materials. Statistical methods of analyzing the historical data of the real technological object and the correlation ...
Natalia Vasilyeva, Ivan Pavlyuk
doaj +1 more source
COMBINED UTILIZATION OF RED MUD AND MECHANICALLY ACTIVATED FLY ASH IN GEOPOLYMERS
This paper focuses on the investigation of the co-utilization of two major industrial waste materials, power station fly ash and red mud. Experimental studies were carried out to establish the correlation between the physical properties of a geopolymer ...
Gábor Mucsi +4 more
doaj +1 more source
Effects of Oxathiapiprolin on the Structure, Diversity and Function of Soil Fungal Community
Pesticides can affect non-target microorganisms in the soil and are directly related to soil microecological health and environmental safety. Oxathiapiprolin is a piperidinyl thiazole isoxazoline fungicide that shows excellent control effect against ...
Yuxuan Chen +9 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source

