Results 61 to 70 of about 2,422,288 (298)

Influence of casting speed on fabricating Al-1%Mn and Al-10%Si alloy clad slab

Science and Engineering of Composite Materials, 2017
In this paper, the effect of casting speed on fabricating Al-1%Mn and Al-10%Si alloy clad slab was investigated. Before the trials with the semi-continuous casting process were conducted, a series of simulation with the engineering software FLUENT was ...
Yu Yingshui, Jie Jinchuan, Sun Jianbo, Li Tingju   +3 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Elaboration of New Method of Deep Processing of Caro-tene-containing Raw Materials Into Nanoadditives with the Use of Cryogenic Freezing and Fine-dispersed Grinding [PDF]

, 2016
The aim of the work is elaboration of principally new cryogenic method of deep processing of carotene-containing vegetable raw material (CCVRM) such as carrot, pumpkin, sweet Bulgarian pepper, tomato, sea buckthorn, apricot using cryogenic freezing and ...
Bilenko, L. (Leonida), Pavlyuk, R. (Raisa), Pogarska, V. (Viktoriya), Stukonozhenko, T. (Tetyana), Timofeyeva, N. (Nadiya)   +4 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Effect of the addition of different forms of rosemary (Rosmarinus officinalis L.) on the quality of vacuum-packed minced pork

Journal of Veterinary Research
Apart from their antioxidant activity, plant-derived bioactive compounds can also positively affect the quality of meat and meat products by improving their sensory and microbiological properties and preventing discolouration.
Śmiecińska Katarzyna, Daszkiewicz Tomasz, Krajewska Agnieszka, Kubiak Dorota   +3 more
doaj   +1 more source

The effect of waste logistics on the environmental impact of road transport [PDF]

, 2008
Nowadays we should consider the wastes in a much wider sense as an expedient raw material source. From a logistic point of view the fact that the flows of the second raw materials are not constant in the waste logistics systems is a challenge.
Kosztyó, Á., Nagy, Z., Török, Ádám
core  

Segmentation-free x-ray energy spectrum estimation for computed tomography

, 2016
X-ray energy spectrum plays an essential role in imaging and related tasks. Due to the high photon flux of clinical CT scanners, most of the spectrum estimation methods are indirect and are usually suffered from various limitations. The recently proposed
Niu, Tianye, Zhang, Qiude, Zhao, Wei
core   +1 more source

The Study of the Method of Fight Against Formation of Polarizing Layer at the Process of Ultrafiltration Concentration of the Skim Milk [PDF]

, 2016
The description of experimental set and the method of processing of the results of the study of the method of fight against formation of polarizing layer in the process of ultrafiltration concentration of skim milk raw material were presented.
Deynychenko, G. (Grygoriy), Guzenko, V. (Vasyl), Melnik, O. (Olga), Omelchenko, A. (Aleksandr), Udovenko, O. (Oleg)   +4 more
core   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source