PRC2.1(PCL2)‐coordinated H3K27me3‐enriched PNH establishes a spatial scaffold crucial for nucleolar integrity. As a crucial coordinator, PCL2 links PRC2.1 to chromatin organization and NPM1 assembly. This network‐based model reveals how chromatin modifications and nucleolar components cooperatively maintain nucleolar architecture, revealing novel ...
Lina Zhu +12 more
wiley +1 more source
Complete genome sequence of <i>Stenotrophomonas</i> sp. strain C-A, isolated from contaminated <i>Pseudomonas putida</i> cultures. [PDF]
Roghair Stroud MN, Halverson LJ.
europepmc +1 more source
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong +14 more
wiley +1 more source
Whole-genome sequencing and annotation of probiotic <i>Bacillus amyloliquefaciens</i> COFCAU_P1. [PDF]
Choudhury TG +5 more
europepmc +1 more source
Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu +17 more
wiley +1 more source
Next-Generation Sequencing Dataset Downloader and In Silico Sequence Mining: Graphical-User-Interface-Based Tools for Accessible, Multiprobe Target Mining in Next-Generation Sequencing Data. [PDF]
Kim MC +9 more
europepmc +1 more source
Neural Fields for Highly Accelerated 2D Cine Phase Contrast MRI
ABSTRACT 2D cine phase contrast (CPC) MRI provides quantitative information on blood velocity and flow within the human vasculature. However, data acquisition is time‐consuming, motivating the reconstruction of the velocity field from undersampled measurements to reduce scan times. In this work, neural fields are proposed as a continuous spatiotemporal
Pablo Arratia +7 more
wiley +1 more source
Hidden Fungal DNA Structures May Shape Sequencing Outcomes. [PDF]
Thomas PW.
europepmc +1 more source
NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider +14 more
wiley +1 more source
The Complete Mitochondrial Genome of <i>Conopomorpha sinensis</i> (Lepidoptera: Gracillariidae) Sample from Taiwan. [PDF]
Kuo YY +4 more
europepmc +1 more source

