Results 11 to 20 of about 6,132,993 (209)
How the strategic review of charges 2002-06 casts a long shadow over future water charges in Scotland [PDF]
, 2006 The findings of the research described in this paper are that there were significant errors made in the setting of water charges in 2002-06 in Scotland, such that there was substantial overcharging of customers. This will continue at a lesser extent over
Cuthbert, Jim, Cuthbert, Margaret
core +3 more sources
Did flaws in the application of resource accounting and budgeting distort the Strategic Review of Water Charges in Scotland? [PDF]
, 2003 In August 2001, the Water Commissioner was tasked by the Scottish Executive to carry out a strategic review of water charges covering the years 2002-06. Based on revenue calculations made by the Water Commissioner in his review, Scottish Water issued its
Cuthbert, Jim, Cuthbert, Margaret
core +3 more sources
The Affordability of Water and Sewerage Charges in Scotland [PDF]
, 2018 Water and sewerage charges are an expense for Scottish consumers. The average annual combined household charge was just under £350 in 2015/16. Water and sewerage bills are determined by council tax band, with higher banded properties paying progressively
Fraser of Allander Institute
core +2 more sources
A rejoinder to Midwinter and Simpson : and how their notes raise further concerns about the financing of the water industry in Scotland [PDF]
, 2007 In separate notes in the last issue of this Commentary, Midwinter and Simpson attempted to allay concerns we had raised about, respectively, the strategic review of water charges for 2002-06 and 2006-10: (Midwinter, 2006 and Simpson, 2006). Here, we show
Cuthbert, Jim, Cuthbert, Margaret
core +2 more sources
How the civil service responded to our proposal for changing the pricing system for Scottish Water [PDF]
, 2011 Water is one of Scotland's most vital and largest industries. It is an input into all other forms of economic activity as well as being part of every family's expenditure. It is therefore important, both for living standards and for the economy, that the
Cuthbert, Jim, Cuthbert, Margaret
core +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
, 2018 Border Archaeology undertook a programme of Archaeological Observation in April 2012 on behalf of Bristol Water in respect of engineering groundworks at Purton Raw Water Reservoir (NGR SO 69567 04140) comprising installation of a replacement raw water ...
Border Archaeology
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source