Syndrome in question: antisynthetase syndrome (anti-PL-7) [PDF]
: Antisynthetase syndrome is a rare autoimmune disease characterized by interstitial lung disease and/or inflammatory myositis, with positive antisynthetase antibodies (anti-Jo-1, anti-PL-7, anti-PL-12, ZO, OJ, anti-KE or KS).
Ana Cláudia Cavalcante Esposito+2 more
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Applying Choosing Wisely: Antinuclear Antibody (ANA) and Sub-Serology Testing in a Safety Net Hospital System. [PDF]
ObjectiveIn 2013, the American College of Rheumatology (ACR) participated in the Choosing Wisely campaign and devised a recommendation to avoid testing antinuclear antibody (ANA) subserologies without a positive ANA and clinical suspicion of disease. The
Davis, Lisa Anne+7 more
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Pain in systemic connective tissue diseases [PDF]
Pain is frequent in patients with connective tissue diseases (CTDs), particularly those affected by systemic sclerosis (SSc) and systemic lupus erythematosus (SLE) in which it is virtually ubiquitous and can have different causes.
Atzeni, Fabiola+4 more
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In systemic sclerosis skin perfusion of hands is reduced and may predict the occurrence of new digital ulcers [PDF]
Systemic sclerosis (SSc) patients are at high risk for the development of ischemic digital ulcers (DUs). The aim of this study was to assess in SSc patients a correlation between skin perfusion evaluated by LDPI and DUs and to evaluate the prognostic ...
Barbano, Biagio+6 more
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Raynaud's is an often-underdiagnosed vascular disorder. Primary Raynaud's (Raynaud's disease) is a result of vasospasm in the absence of underlying disorder, while Raynaud's phenomenon (RP) occurs secondary to an autoimmune process. Raynaud's disease and
S. Christopher Frontario+3 more
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A case of antisynthetase syndrome with chilblains‐like lesions and microangiopathy
We present the case of a 50‐year‐old woman with febrile myalgia, chilblains‐like lesions, and cough. Antinuclear antibodies and anti‐PL‐12 antisynthetase autoantibodies were found in complementary examinations.
Tom Abrassart+3 more
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Negative association of the chemokine receptor CCR5 d32 polymorphism with systemic inflammatory response, extra-articular symptoms and joint erosion in rheumatoid arthritis [PDF]
Introduction Chemokines and their receptors control immune cell migration during infections as well as in autoimmune responses. A 32 bp deletion in the gene of the chemokine receptor CCR5 confers protection against HIV infection, but has also been ...
Arnold, Sybille+6 more
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Acrocyanosis, digital ischemia and acronecrosis as first manifestations of endometrial adenocarcinoma: case presentation and literature review [PDF]
The association between digital ischemia and cancer is rarely reported in literature and the exact mechanism of this occurrence has not been completely understood.
LO RUSSO, Giuseppe+4 more
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Differential diagnosis of rheumatic manifestations of acromegaly. Case report [PDF]
Acromegaly is a chronic endocrine disease characterized by excessive secretion of growth hormone, which, in turn, leads to an increase in the secretion of insulin-like growth factor 1 in the liver.
Margarita A. Perepelova+6 more
doaj +1 more source
Bingyue Xin, Keyue Xie, Bing Huang, Ming Yao Department of Anesthesiology and Pain Research Center, The First Hospital of Jiaxing or The Affiliated Hospital of Jiaxing University, Jiaxing, People’s Republic of ChinaCorrespondence: Ming Yao, Department of
Xin B, Xie K, Huang B, Yao M
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