Results 41 to 50 of about 12,566 (221)

Serum Type I Interferon Score for Prediction of Clinically Meaningful Disease Progression in Limited Cutaneous Systemic Sclerosis

open access: yesArthritis &Rheumatology, EarlyView.
Objective To assess the value of serum type I interferon (IFN) score in predicting clinically meaningful progression in limited cutaneous systemic sclerosis (lcSSc) using a novel composite endpoint adopted from the MINIMISE clinical trial. Methods A retrospective, longitudinal lcSSc cohort was identified within a national, multicenter observational ...
Stefano Di Donato   +9 more
wiley   +1 more source

Raynaud's phenomenon in an adolescent girl: A case report

open access: yesIndian Journal of Paediatric Dermatology, 2021
Introduction: Triphasic color change of the distal extremities in response to cold and emotional stress is known as Raynaud's phenomenon (RP). Fingers, toes, nose, and ears are the commonly affected organs.
Rajkumar Motiram Meshram   +3 more
doaj   +1 more source

Advances in Mechanochemical Methods for One‐Pot Multistep Organic Synthesis

open access: yesChemistry – A European Journal, Accepted Article.
Mechanochemical synthesis has emerged as a powerful and more sustainable alternative to conventional solution‐based methods, offering advantages such as no or only minimal solvent use, reduced reaction times, and simplified operational conditions.
Michael Schnürch, Nina Biedermann
wiley   +1 more source

Uncommon skeletal findings in systemic sclerosis (scleroderma)

open access: yesSouth African Journal of Radiology, 2002
Scleroderma or progressive systemic sclerosis is a diffuse disease characterised by excessive deposition of collagen and small-vessel arteritis. Systemic sclerosis is divided into two groups. 1.
Betsie van der Walt   +2 more
doaj   +1 more source

No effects of bosentan on microvasculature in patients with limited cutaneous systemic sclerosis [PDF]

open access: yes, 2009
The endothelium-derived vasoconstrictor molecule endothelin-1 (ET-1) has been suggested to play a role in the pathogenesis of Raynaud's phenomenon (RP) and systemic sclerosis (SSc).
Andries J. Smit   +5 more
core   +2 more sources

A case of idiopathic mesenteric phlebosclerosis: Insight into pathogenesis of associated vascular calcification

open access: yesJournal of General and Family Medicine, EarlyView.
Abstract A 75‐year‐old woman had been taking a geniposide‐containing herbal medicine for 7 years and was admitted to our hospital for nausea, abdominal pain, and distention. CT revealed colonic wall thickening, whereas CS revealed a dark‐purple edematous mucosa. Furthermore, biopsy specimens revealed small vein hyalinization.
Kimitoshi Kubo, Noriko Kimura
wiley   +1 more source

Raynaud's of the tongue [PDF]

open access: yes, 2017
We describe a 40-year-old lady who presents with a painful white tongue on exposure to the cold. The differential diagnosis and investigations are outlined with a discussion about this unusual presentation of a common ...
Nawaz, Zainab   +2 more
core   +4 more sources

Skin Diseases in Long‐Distance Runners

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Long‐distance running, including both road running and trail/mountain running, has significantly increased in popularity in recent years. The prolonged, repetitive physical activity combined with environmental exposures predisposes runners to a range of dermatological problems.
Henna Ahomies   +3 more
wiley   +1 more source

Management of Endothelial Dysfunction in Systemic Sclerosis: Current and Developing Strategies

open access: yesFrontiers in Medicine, 2021
Systemic Sclerosis (SSc) is an autoimmune disease marked by dysregulation of the immune system, tissue fibrosis and dysfunction of the vasculature. Vascular damage, remodeling and inadequate endothelial repair are hallmarks of the disease.
Djúlio César Zanin-Silva   +7 more
doaj   +1 more source

Predictors of systemic sclerosis patients with interstitial lung disease progression: A retrospective study

open access: yesRheumatology &Autoimmunity, EarlyView.
The final systemic sclerosis patients with interstitial lung disease (SSc‐ILD) progression prediction model was composed of 6 significant risk factors: male, type 2 diabetes mellitus, pericardial effusion, anti‐Ro52, hypoproteinemia, and elevated C‐reactive protein. Our model demonstrated excellent prognostic utility.
Xi Cao   +6 more
wiley   +1 more source

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