Results 121 to 130 of about 22,485 (285)

Evaluating heterogeneity in MDA‐5+ dermatomyositis through cluster analyses

open access: yes
Journal of the European Academy of Dermatology and Venereology, EarlyView.
David R. Pearson
wiley   +1 more source

Differences in IgG Sialylation Distinguish Asymptomatic From Symptomatic Antinuclear Antibody–Positive Individuals

open access: yesArthritis &Rheumatology, Volume 78, Issue 1, Page 243-254, January 2026.
Objective The transition from asymptomatic antinuclear antibody (ANA) positivity to systemic autoimmune rheumatic disease (SARD) is associated with increased production of proinflammatory factors such as tumor necrosis factor α (TNFα). Here we investigate whether the relative absence of inflammation in asymptomatic ANA+ individuals (ANA+NS) results ...
Carolina Muñoz‐Grajales   +8 more
wiley   +1 more source

A Case of Atrial Septal Defect Unveiled by the Treatment for Pulmonary Arterial Hypertension

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT We present a case of a 51‐year‐old woman with atrial septal defect (ASD) masked by pulmonary arterial hypertension (PAH). Three months after PAH treatment with a combination of endothelin receptor antagonist and phosphodiesterase five inhibitor, the transthoracic echocardiography revealed left‐to‐right shunting through a secundum ASD.
Takaaki Fujii   +12 more
wiley   +1 more source

Antiphospholipid Syndrome Coexisting With Evans Syndrome and SCL‐70 Antibody Positivity: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT This case of antiphospholipid syndrome, Evans syndrome, and anti‐Scl‐70 positivity (suggesting early SSc) showed marked symptom improvement with rituximab, but poor prognosis persists. Highlights the need for early diagnosis of overlapping autoimmunity, SSc complication monitoring, and optimized immunotherapy in complex cases.
Chunhua Cao   +4 more
wiley   +1 more source

Beyond Raynaud's: Atypical Peripheral Vascular Manifestations in a Case of CREST Syndrome

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Peripheral vascular disease (PVD) is a rare but severe symptom of CREST syndrome, which itself is a limited cutaneous sclerosis. Even though Raynaud's phenomenon is the gold standard of CREST, the development of critical limb ischemia and self‐amputation is rare.
Sakshi Kumari   +4 more
wiley   +1 more source

When Autoimmunity Meets Malignancy: A Rare Case of Concomitant Systemic Lupus and Multiple Myeloma

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT The association between systemic lupus erythematosus (SLE) and multiple myeloma (MM) is rare, with fewer than 20 cases reported in the literature, raising questions about the link between chronic immune dysregulation and oncogenesis. We report the case of a 43‐year‐old Malagasy woman in whom a monoclonal β2‐globulin spike, incidentally ...
Solohery Jean Noël Ratsimbazafy   +7 more
wiley   +1 more source

Fenómeno de Raynaud Raynaud's Phenomenon

open access: yesAngiologia e Cirurgia Vascular, 2011
O Fenómeno de Raynaud (FR) é uma manifestação clínica comum, traduzida por vasoespasmos recorrentes dos dedos, na maioria das vezes provocados pela exposição ao frio ou estímulos emocionais. Pode ser primário (idiopática) ou secundária a diversas doenças
Ivone Silva   +5 more
doaj  

Early Onset Heart Failure due to RBM20 Variant: A Case Report Emphasizing Genetic Diagnosis and Arrhythmic Risk Stratification

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
Transthoracic echocardiography demonstrating biventricular dilatation. Parasternal long‐ and short‐axis views and apical four‐ and two‐chamber views show marked left ventricular dilatation with increased end‐diastolic volume, associated with right ventricular dilatation.
Cristian Orlando Porras Bueno   +3 more
wiley   +1 more source

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