Results 21 to 30 of about 22,485 (285)

Algorithm for the Diagnosis of Scleroderma. Early Systemic Sclerosis: Definitions and diagnostic criteria

Italian Journal of Medicine, 2013
Introduction: The term scleroderma derives from the Greek words skleros, which means hard, and derma, which means skin. It refers to an acquired systemic inflammatory disease of the connective tissue –also known as systemic sclerosis (SSc)– characterized
Domenico Galasso, Salvatore Mazzuca, Norma Marigliano   +2 more
doaj   +1 more source

Calcium Channel Blockers and Esophageal Sclerosis: Should We Expect Exacerbation of Interstitial Lung Disease

Case Reports in Gastroenterology, 2012
Esophageal sclerosis is the most common visceral manifestation of systemic sclerosis, resulting in impaired esophageal clearance and retention of ingested food; in addition, co-existence of lung fibrosis with esophageal scleroderma is not uncommon.
Charalampos Seretis, Fotios Seretis, George Gemenetzis, Nikolaos Liakos, Apostolos Pappas, Stavros Gourgiotis, Emmanuel Lagoudianakis, Dimitrios Keramidaris, Nikolaos Salemis   +8 more
doaj   +1 more source

Systemic lupus erythematosus and Raynaud's phenomenon [PDF]

Anais Brasileiros de Dermatologia, 2015
: BACKGROUND: Patients with systemic lupus erythematosus seem to belong to different serological and clinical subgroups of the disease. Genetic background can cause the appearance of these subgroups.
Flavia Emilie Heimovski, Juliana A. Simioni, Thelma Larocca Skare   +2 more
doaj   +2 more sources

Eosinophilic fasciitis (Shulman's disease): review and comparative evaluation of seven patients. [PDF]

, 2019
OBJECTIVES: Eosinophilic fasciitis (EF) was described in 1974 by Shulman as a rare fibrosing connective tissue disease of unknown etiology. An undetermined trigger is thought to lead to the degranulation of eosinophils that interact with fibroblasts and
Cimbron, M, Farinha, F, Mendonça, T, Urzal, J   +3 more
core   +1 more source

Anti-Eukaryotic Initiation Factor 2B-Positive Systemic Sclerosis-Associated Interstitial Lung Disease With Progressive Fibrosis: A Case Report. [PDF]

Respirol Case Rep
We report the case of a patient with anti‐eIF2B‐positive SSc‐ILD managed with stepwise mycophenolate titration and subsequent nintedanib addition, accompanied by serial biomarkers and clinical follow‐up to help delineate the therapeutic course within this rare serological phenotype.
Ikeda H, Tachikawa R, Sasada T, Sumitomo S.   +3 more
europepmc   +2 more sources

Bloqueio do receptor de leucotrieno CysLT1 em pacientes com fenômeno de Raynaud: evidência capilaroscópica do papel do leucotrieno CysLT1 receptor inhibition in patients with Raynaud's phenomenon: capillaroscopic evidence of the role of leukotriene

Revista Brasileira de Reumatologia, 2012
OBJETIVO: Avaliar a ação do medicamento inibidor do receptor de leucotrieno CysLT1 (montelucaste) nas alterações vasculares das mãos em pacientes com fenômeno de Raynaud.
Mario Newton Leitão de Azevedo, Edda Maria T Bernardini, Elizabeth F Salles, Felipe Heinzmann, Frederico Marconde, Tatiana Mello, Blanca Elena Rios Gomes   +6 more
doaj   +1 more source

ISME-incoherent sampling of multi-echo data to minimize cardiac-induced noise in brain maps of $$ {R}_2^{\ast } $$ and magnetic susceptibility. [PDF]

Magn Reson Med
Abstract Purpose Maps of the MRI parameters R2*$$ {\mathrm{R}}_2^{\ast } $$ and magnetic susceptibility (χ$$ \chi $$) enable the investigation of microscopic tissue changes in brain disease. However, cardiac‐induced signal instabilities increase the variability of brain maps of R2*$$ {\mathrm{R}}_2^{\ast } $$ and χ$$ \chi $$.
Raynaud Q, Oliveira R, Corbin N, Balbastre Y, van Heeswijk RB, Lutti A.   +5 more
europepmc   +2 more sources

Genetic Susceptibility to Antisynthetase Syndrome Associated With Single-Nucleotide Variants in the IL1B Gene That Lead Variation in IL-1β Serum Levels

Frontiers in Medicine, 2020
The antisynthetase syndrome (ASSD) is an autoimmune disorder characterized by myositis, arthritis, mechanic's hands, fever, Raynaud phenomenon, and interstitial lung disease (ILD).
Marco Antonio Ponce-Gallegos, Espiridión Ramos-Martínez, Adriana García-Carmona, Mayra Mejía, Karol J. Nava-Quiroz, Gloria Pérez-Rubio, Enrique Ambrocio-Ortiz, Montserrat I. González-Pérez, Ivette Buendía-Roldán, Jorge Rojas-Serrano, Ramcés Falfán-Valencia   +10 more
doaj   +1 more source

Antisynthetase Syndrome in a Patient with Pulmonary Embolism and Nonbacterial Thrombotic Endocarditis

Case Reports in Rheumatology, 2023
Antisynthetase syndrome is a rare autoimmune disease within the subset of idiopathic inflammatory myopathies. The diagnostic criteria include the presence of an aminoacyl-tRNA synthetase antibody, and typical clinical findings, including myositis ...
Anusha Vege, Jesse Beery, Areeba Kara
doaj   +1 more source

Pulmonary vasospasm in systemic sclerosis: noninvasive techniques for detection [PDF]

, 2014
In a subgroup of patients with systemic sclerosis (SSc), vasospasm affecting the pulmonary circulation may contribute to worsening respiratory symptoms, including dyspnea.
Giannarou, S, Hansell, DM, Keir, GJ, MacDonald, P, Nair, A, Oldershaw, P, Wells, AU, Wort, SJ, Yang, G-Z   +8 more
core   +1 more source