Results 181 to 190 of about 3,783 (267)

Fifteen Years of Health-and-Environment Research in Slovenia. [PDF]

Zdr Varst
Carli T, Kukec A, Zaletel-Kragelj L, Eržen I.   +3 more
europepmc   +1 more source

Phenylalanine Versus Tyrosine (Pos. 367/332 in MCT1/MCT4) in the Substrate Binding Site Defines Affinity and Preferred Directionality of Human Monocarboxylate Transporters 1–4

Acta Physiologica, Volume 242, Issue 7, July 2026.
ABSTRACT Aim Human monocarboxylate transporters 1–4, MCT, are key for the lactate/H+ exchange between glycolytic and oxidative cancer cells, white and red muscle fibers, or in the astrocyte‐neuron shuttle. The common MCT transport mechanism involves three conserved residues, that is, a substrate‐attracting Lys and a conformation‐locking Asp/Arg salt ...
Maike Menzel, Ioana‐Daniela Dumitru, Josh Peters, Jan‐Bernd Hövener, Andrey N. Pravdivtsev, Ana‐Nicoleta Bondar, Eric Beitz   +6 more
wiley   +1 more source

Aboveground and belowground sizes are aligned in the unified spectrum of plant form and function. [PDF]

Nat Commun
Beccari E, Carmona CP.
europepmc   +1 more source

Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice

Brain Pathology, Volume 36, Issue 4, July 2026.
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga, Eva Fernández‐Muñoz, Jorge M. Charco, Enric Vidal, Diego Herrero‐Martínez, Josu Galarza‐Ahumada, Cristina Sampedro‐Torres‐Quevedo, Samanta Giler, Mariví Geijo, Gloria González‐Aseguinolaza, Hasier Eraña, Joaquín Castilla   +11 more
wiley   +1 more source

Reasons for the Intention to Leave among Nurses Working in Internal Medicine and Surgery Departments of Slovenian Hospitals - A Cross Sectional Study. [PDF]

Zdr Varst
Skela-Savič B, Sermeus W, Bahun M, Pivač S, Albreht T.   +4 more
europepmc   +1 more source

The L108I polymorphism in mouse prion protein drives spontaneous disease and enhances transmission of atypical and classical prion strains

Brain Pathology, Volume 36, Issue 4, July 2026.
A single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Hasier Eraña, Enric Vidal, Natalia Fernández‐Borges, Jorge M. Charco, Carlos M. Díaz‐Domínguez, Cristina Sampedro‐Torres‐Quevedo, Josu Galarza‐Ahumada, Eva Fernández‐Muñoz, Maitena San‐Juan‐Ansoleaga, Miguel Ángel Pérez‐Castro, Nuno Gonçalves‐Anjo, Patricia Piñeiro, Samanta Giler, Nora González‐Martín, Nuria L. Lorenzo, Africa Manero‐Azua, Guiomar Perez de Nanclares, Mariví Geijo, Manuel A. Sánchez‐Martín, Jesús R. Requena, Joaquín Castilla   +20 more
wiley   +1 more source

Deficiency of Toll-like receptor 2 is a driver of sex-related compositional and structural rearrangements of membrane lipids. [PDF]

Commun Chem
Ica RS, Mlinac-Jerkovic K, Stojanović M, Roxana Biricioiu M, Puljko B, Maček-Hrvat N, Radmilović MD, Korade Ž, Mirnics K, Clemmer DE, Zamfir AD, Kalanj-Bognar S.   +11 more
europepmc   +1 more source

Applications of ChatGPT in the Health Sector: A Systematic Literature Review

Expert Systems, Volume 43, Issue 7, July 2026.
ABSTRACT The integration of large language models, particularly ChatGPT, into healthcare has attracted increasing attention due to their potential to support medical education, clinical decision‐making, administrative workflows, patient communication and clinical documentation.
Alejandro Martínez‐Burgos, Elena Enamorado‐Díaz, Javier Jesús Gutiérrez‐Rodríguez, Julián A. García‐García   +3 more
wiley   +1 more source

The Evolution and Challenges of Academic Family Medicine: Insights from the Banja Luka Declaration. [PDF]

Zdr Varst
Stepanović A, Švab I, Đukić B, Škrbić R.   +3 more
europepmc   +1 more source