A mechanistic model of cross-bridge migration in RBC aggregation and disaggregation [PDF]
Frontiers in Bioengineering and Biotechnology, 2022 Red blood cells (RBCs) clump together under low flow conditions in a process called RBC aggregation, which can alter RBC perfusion in a microvascular network.
Swe Soe Maung Ye, Sangho Kim
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Multiple and Periodic Measurement of RBC Aggregation and ESR in Parallel Microfluidic Channels under On-Off Blood Flow Control [PDF]
Micromachines, 2018 Red blood cell (RBC) aggregation causes to alter hemodynamic behaviors at low flow-rate regions of post-capillary venules. Additionally, it is significantly elevated in inflammatory or pathophysiological conditions.
Yang Jun Kang, Byung Jun Kim
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Microfluidic-Based Technique for Measuring RBC Aggregation and Blood Viscosity in a Continuous and Simultaneous Fashion [PDF]
Micromachines, 2018 Hemorheological properties such as viscosity, deformability, and aggregation have been employed to monitor or screen patients with cardiovascular diseases.
Yang Jun Kang
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Higher Daily Physical Activity Level Is Associated with Lower RBC Aggregation in Carotid Artery Disease Patients at High Risk of Stroke [PDF]
Frontiers in Physiology, 2017 Aim: Carotid artery disease (CAD) is an atherosclerotic inflammatory disease that affects the arterial wall, specifically at points of bifurcation where blood flow is disturbed. Abnormal blood rheology could participate in the pathophysiology of ischemic
Pauline Mury +24 more
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Microfluidic-Based Biosensor for Sequential Measurement of Blood Pressure and RBC Aggregation Over Continuously Varying Blood Flows [PDF]
Micromachines, 2019 Aggregation of red blood cells (RBCs) varies substantially depending on changes of several factors such as hematocrit, membrane deformability, and plasma proteins. Among these factors, hematocrit has a strong influence on the aggregation of RBCs.
Yang Jun Kang
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Enhanced RBC Aggregation in Type 2 Diabetes Patients. [PDF]
J Clin Lab Anal, 2015 BackgroundThis study aimed to investigate the relationship between HbA1c and RBC aggregation in type 2 diabetes mellitus (T2DM) patients by analysis of data from routine clinical tests and from in vitro experiments.MethodsA total of 2,111 inpatients with type 2 diabetes were selected and among them, 364 patients (Group A) had limited influence of ...
Li Q, Li L, Li Y.
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A Microfluidic Method for Simultaneous Assessment of Blood Viscosity and Red Blood Cell Aggregation During Continuous Syringe Delivery [PDF]
SensorsAccurate assessment of blood viscosity and red blood cell (RBC) aggregation under continuous flow is important for hemorheological analysis. However, simultaneous measurement remains challenging because both properties are influenced by flow conditions ...
Yang Jun Kang
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Applied Sciences, 2020 Red blood cell (RBC) aggregation highly influences hemorheology and blood microcirculation in the human body. The aggregation properties of RBCs can vary due to numerous factors, including RBC age.
Petr Ermolinskiy +6 more
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Altered RBC aggregability in diabetes: a threshold for pathophysiological structure-function RBC changes. [PDF]
Cardiovasc Diabetol Endocrinol RepAbstract Objective Vascular complications have been associated with pathophysiological RBC changes including reduced RBC deformability (RBCD): the ability of RBCs to change their shape in the microvasculature and increased red blood cell aggregability (RBCA): the tendency of RBCs to form ...
Ebenuwa I +10 more
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Micro Blood Flow-Resolved Rheometry [PDF]
MicromachinesFor effectively assessing blood, red blood cell (RBC) aggregation and blood viscosity have been measured in microfluidic environments. However, the previous methods still face several challenges (dead-volume loss, RBC sedimentation, hematocrit-sensitive ...
Yang Jun Kang
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