Results 91 to 100 of about 16,582 (245)

Multifunctional Adhesive Hydrogel for Rapid Cardiac Hemostasis and Antibacterial Protection

Advanced Materials Technologies, EarlyView.
A multifunctional polyacrylamide/gelatin/tannic acid hydrogel (PGT) is presented for rapid cardiac hemostasis under wet, dynamic conditions. Surface tannic acid coating enables instantaneous wet adhesion, accelerates coagulation, and confers antibacterial activity within a single platform.
Seoha Kim, Kaeun Chae, Inseon Kim, Kye Il Joo, Chang Sup Kim, Seunghun S. Lee   +5 more
wiley   +1 more source

Optically Active Birefringent Polymer–Lipid Hybrid Microparticles With Dual‐Stimuli Responsiveness

Advanced Optical Materials, EarlyView.
The present study reports on geometrically tunable, magnetic and NIR‐stimuli‐responsive anisotropic microparticles that exhibit intrinsic birefringence due to their lamellar crystalline architecture, enabling label‐free detection under a polarized light.
Burcu Okmen Altas, Emre Bukusoglu, Nihal Aydogan   +2 more
wiley   +1 more source

Microfluidic Chip for Quantitatively Assessing Hemorheological Parameters

Micromachines
The biomechanical properties of blood are regarded as promising biomarkers for monitoring early-stage abnormalities and disease progression. To detect any changes in blood, it is necessary to measure as many rheological properties as possible.
Yang Jun Kang
doaj   +1 more source

Additional file 1 of Altered RBC aggregability in diabetes: a threshold for pathophysiological structure-function RBC changes

Supplementary Material ...
Ebenuwa, Ifechukwude, Violet, Pierre-Christian, Teng, Stephanie, Greene, Thom, Munyan, Nicholas, Berman, Razi, Rozga, Irene, Walter, Mary, Wilkins, Kenneth J., Parrow, Nermi, Levine, Mark   +10 more
openaire   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

COVID-19 impairs oxygen delivery by altering red blood cell hematological, hemorheological, and oxygen transport properties

Frontiers in Physiology
Introduction: Coronavirus disease 2019 (COVID-19) is characterized by impaired oxygen (O2) homeostasis, including O2 sensing, uptake, transport/delivery, and consumption. Red blood cells (RBCs) are central to maintaining O2 homeostasis and undergo direct
Stephen C. Rogers, Mary Brummet, Zohreh Safari, Qihong Wang, Tobi Rowden, Tori Boyer, Allan Doctor   +6 more
doaj   +1 more source

Stromal‐Derived IL‐8 Promotes M2 Macrophage Polarization via the RhoA/MRTF‐A/SRF Transcriptional Axis to Impair CD8+ T Cell Cytotoxicity in Lung Cancer

Advanced Science, EarlyView.
In the recondite pulmonary neoplastic milieu, DESMIN+ cancer‐associated fibroblasts function as the paramount stromal source of IL‐8, precipitating a deleterious immunological metamorphosis by engaging CXCR2 receptors on the myeloid lineage. This paracrine stimulus triggers a mechanotransduction cascade characterized by RhoA‐dependent actin ...
Xuyu Gu, Qiyu Fang, Jia Yu, Ting Yu, Huashan Shi, Kaiqi Jin, Lei Jiang, Wentian Zhang   +7 more
wiley   +1 more source

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang, Chen Kan, Xinhui Yang, Yajuan Hao, Xuemin Cai, Mei Yang, Qianqian Zhang, Zhengting Wang, Ning Jiang, Lei Wang, Hua‐Bing Li, Jing Zhou   +11 more
wiley   +1 more source

A Pulsatile Flow-Modulation Microfluidic Sensor for Simultaneous Monitoring of Red Blood Cell Aggregation and Viscosity-Sensitive Time Constant

Sensors
Red blood cell (RBC) aggregation and viscosity-related flow resistance are important hemorheological parameters for assessing blood flow abnormalities, but their simultaneous measurement often requires multiple pumps or intermittent flow stoppage.
Yang Jun Kang
doaj   +1 more source

Tropomyosin 1 Promotes Platelet Adhesion and Clot Contraction Separate from Its Roles in Developmental Hematopoiesis

Advanced Science, EarlyView.
ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung, Victor Tsao, Alina D Peshkova, Oscar A. Marcos‐Contreras, Kim Ha, Brian M Dulmovits, Nkemdilim Okoli, Anvi Sinha, Gennadiy Fonar, Rong Qiu, Rolf D Bates, Janelle Yeboah, Carson Shalaby, Tyler Truex, Soomin Jeong, Edna C Hardeman, Peter W Gunning, Vladimir R Muzykantov, Jacob W Myerson, Christopher S Thom   +19 more
wiley   +1 more source