Results 21 to 30 of about 25,894 (290)
Journal of Cell Science, 2004 A key component of the machinery that regulates cell cycle entry and progression in mammalian cells is the retinoblastoma protein (Rb), which functions as a barrier to inappropriate cell cycle progression.
openaire +2 more sources
The Effects of Reduced Beam Section on Castellated Beam
MATEC Web of Conferences, 2017 This paper presents reduced beam section (RBS) technique on castellated beam. Aim of this study is to ensure the plastic moment reach far from column face without significant of strength decreasing.
H Aswad Nini +3 more
doaj +1 more source
Buildings, 2023 A rubber isolation bearing installed in a staircase (RBS) was proposed to mitigate seismic damages to the component of staircases and improve their seismic performance.
Liang Bai +5 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Cell Reports, 2019 Summary: Antibodies targeting the receptor binding site (RBS) of the influenza virus hemagglutinin (HA) protein are usually not broadly reactive because their footprints are typically large and extend to nearby variable HA residues.
Seth J. Zost +10 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Nanomaterials, 2020 Since pits and fissures are the areas most commonly affected by caries due to their structural irregularity, bioactive resin-based sealant (RBS) may contribute to the prevention of secondary caries. This study aims to investigate the mechanical, physical,
Myung-Jin Lee +6 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Beilstein Journal of NanotechnologyPrecise control of electrical conductivity, humidity sensitivity, and photocatalytic activity in polymeric and carbon-based materials is essential for advancing technologies in environmental sensing, flexible electronics, and photocatalytic systems ...
Josef Novák +6 more
doaj +1 more source