Results 31 to 40 of about 19,635 (295)

Establishment of hepatitis C virus RNA-replicating cell lines possessing ribavirin-resistant phenotype.

open access: yesPLoS ONE, 2015
BackgroundRibavirin (RBV) is a potential partner of interferon-based therapy and recently approved therapy using direct acting antivirals for patients with chronic hepatitis C.
Shinya Satoh   +6 more
doaj   +1 more source

The resource-based view: a tool of key competency for competitive advantage [PDF]

open access: yesProblems and Perspectives in Management, 2019
The increasing turmoil in the external organizational setting or business environment has focused attention on capabilities and resources as the primary source of competitive advantage.
Akwesi Assensoh-Kodua
doaj   +1 more source

Interferon convencional versus interferon peguilado associados à ribavirina no tratamento de pacientes coinfectados pelo vírus da hepatite C (genótipo 1) e da imunodeficiência humana Alpha-interferon versus peg-interferon associated to ribavirin in the treatment of genotype 1 hepatitis C virus and human imunodeficiency virus coinfected patients

open access: yesArquivos de Gastroenterologia, 2009
CONTEXTO: Tem sido sugerido que os pacientes coinfectados por vírus da hepatite C e da imunodeficiência humana (VHC/HIV) devam ser tratados com interferon peguilado associado à ribavirina (PEG+RBV) porque as taxas de resposta virológica sustentada seriam
Paulo Roberto Lerias de Almeida   +5 more
doaj   +1 more source

Advanced Development of the rF1V and rBV A/B Vaccines: Progress and Challenges [PDF]

open access: yesAdvances in Preventive Medicine, 2012
The development of vaccines for microorganisms and bacterial toxins with the potential to be used as biowarfare and bioterrorism agents is an important component of the US biodefense program. DVC is developing two vaccines, one against inhalational exposure to botulinum neurotoxins A1 and B1 and a second forYersinia pestis, with the ultimate goal of ...
Hart, Mary Kate   +3 more
openaire   +2 more sources

Unified Pressure and Field Response Across Distinct Charge‐Order Regimes in Ti‐Doped CsV3Sb5

open access: yesAdvanced Functional Materials, EarlyView.
We microscopically investigate the interplay between charge order and superconductivity in a kagome superconductor across regimes of long‐ and short‐range charge order. Hydrostatic‐pressure and magnetic‐field μSR$\mu{\rm SR}$ measurements reveal remarkably similar superconducting and normal‐state time‐reversal‐symmetry‐breaking responses in both ...
P. Kral   +12 more
wiley   +1 more source

The pathophysiology of fluid removal during haemodialysis: implications for blood volume monitoring and determination of dry weight. [PDF]

open access: yes, 2007
The aim of the research was to characterise the pathophysiology of ultrafiltration (UF) during haemodialysis (HD) using a range of assessment tools. The hypothesis was that objective monitoring would facilitate accurate estimation of dry weight (DW) and ...
Mitra, S., Mitra, Sandip
core  

Renal Clearable Luminogenic Reporter for Ultrasensitive Influenza Virus Imaging and Efficient Antiviral Therapies Monitoring in Living Mice

open access: yesAdvanced Science, EarlyView.
A viral luminogenic reporter with chemiluminescence/fluorescence dual‐response and efficient renal clearance was developed for non‐invasive imaging and urinalysis of H1N1 virus protease, allowing for remote detection of H1N1 virus infections and monitoring of antiviral therapeutic efficacy in living mice.
Bankang Ruan   +9 more
wiley   +1 more source

Reduced ITPase activity and favorable IL28B genetic variant protect against ribavirin-induced anemia in interferon-free regimens.

open access: yesPLoS ONE, 2018
BackgroundGenetic variants of inosine triphosphatase (ITPA) that confer reduced ITPase activity are associated with protection against ribavirin(RBV)-induced hemolytic anemia in peginterferon(IFN)/RBV-based treatment of hepatitis C virus (HCV).
Aparna Vasanthakumar   +8 more
doaj   +1 more source

SVR by RBV.

open access: yes, 2018
The figure shows Sustained Virological Response (SVR) rates with (1) or without (2) RBV in patients treated with SOF/DCV (A) or with SOF/DCV (B).
Domenico Potenza (5575022)   +13 more
core   +1 more source

Mapping the Innovation DNA of Agribusiness Firms: A Multi‐Method Analysis of Strategic Capabilities and Performance

open access: yesAgribusiness, EarlyView.
ABSTRACT Innovation is essential for competitiveness in agribusiness facing dynamic environments. This study examines how market orientation, marketing, relational, and social capabilities influence innovation performance. Using data from 751 Spanish firms and a multi‐method approach that integrates Structural Equation Modeling (PLS‐SEM), Necessary ...
Beatriz Corchuelo Martínez‐Azúa   +1 more
wiley   +1 more source

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