Results 61 to 70 of about 213,523 (100)

Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies

Scientific Data, 2014
Using a genome-scale, lentivirally delivered shRNA library, we performed massively parallel pooled shRNA screens in 216 cancer cell lines to identify genes that are required for cell proliferation and/or viability.
G. Cowley, B. Weir, F. Vazquez, P. Tamayo, Justine A Scott, S. Rusin, Alexandra East-Seletsky, L. Ali, William F. J. Gerath, S. Pantel, P. Lizotte, G. Jiang, Jessica Hsiao, Aviad Tsherniak, Elizabeth Dwinell, Simon Aoyama, M. Okamoto, W. Harrington, Ellen T. Gelfand, Thomas M Green, Mark J Tomko, Shuba Gopal, T. Wong, Hubo Li, Sara Howell, Nicolas Stransky, T. Liefeld, Dongkeun Jang, J. Bistline, Barbara Hill Meyers, S. Armstrong, Ken C. Anderson, K. Stegmaier, Michael Reich, D. Pellman, J. Boehm, J. Mesirov, T. Golub, D. Root, W. Hahn   +39 more
semanticscholar   +1 more source

Clinical Characteristics and Prognostic Predictors of Pneumocystis Jirovecii Pneumonia in Patients with and without Chronic Pulmonary Disease: A Retrospective Cohort Study

Infection and Drug Resistance
Qiuyue Feng,1,2 Zhaohui Tong1 1Department of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing, 100020, People’s Republic of China; 2Department of Respiratory
Feng Q, Tong Z
doaj  

Immune Dysfunction-Associated Elevated RDW, APACHE-II, and SOFA Scores Were a Possible Cause of 28-Day Mortality in Sepsis Patients

Infection and Drug Resistance
Jing Wang,1,* Lisha He,2,* Zhiyan Jin,1,* Guoguang Lu,1 Sufei Yu,1 Lingling Hu,1 Meidan Fang,1 Xiaxia Jin1 1Department of Clinical Laboratory, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Taizhou ...
Wang J, He L, Jin Z, Lu G, Yu S, Hu L, Fang M, Jin X   +7 more
doaj  

Virome analysis of field-collected chilli samples reveals diverse viruses

Virology Journal
Background Chilli (Capsicum annuum L.), an important spice crop, is susceptible to diverse viral infections. Traditional detection methods including PCR and its variants had difficulty in identifying the complete spectrum of viruses, especially in mixed ...
Vamsidhar Reddy Netla, Shridhar Hiremath, Mantesh Muttappagol, H. D. Vinay Kumar, S. Koti Prasanna, T. L. Mohan Kumar, C. R. Jahir Basha, V. Venkataravanappa, K. S. Shankarappa, M. N. Maruthi, C. N. Lakshminarayana Reddy   +10 more
doaj   +1 more source

Investigating how dengue virus-induced metabolic changes affect the host immune response and how to develop Immunomodulatory strategies

Virology Journal
Dengue virus (DENV) infection imposes a significant global health burden, driven by its ability to manipulate host cellular processes to facilitate replication and evade immune defenses.
Fatemeh Amini Chermahini, Pooria Mohammadi Arvejeh, Francesco M. Marincola, Sajjad Ahmad, Ramtin Naderian, Omid Pajand, Majid Eslami, Maliheh Hasannia, Samira Sanami   +8 more
doaj   +1 more source

Business analytics in healthcare operations and the use of mobile applications for decision making by health professionals [PDF]

, 2021
Panagiota, Galetsi
core  

HIV susceptibility to second-generation integrase strand transfer inhibitors among people with multidrug resistance: a systematic review and meta-analysis protocol

Therapeutic Advances in Infectious Disease
Background: With the rapid scale-up of dolutegravir-based regimens, there is a declining trend of HIV drug resistance in several resource-limited settings.
Vincent Kamaël Mekel, Ezechiel Ngoufack Jagni Semengue, Aude Christelle Ka’e, Alex Durand Nka, Collins Ambe Chenwi, Hugues Germain Mimfe’e Mba, Naomi-Karell Etame, Aurelie Minelle Kengni Ngueko, Audrey Rachel Mundo Nayang, Bouba Yagai, Desiré Takou, Maria Mercedes Santoro, Nicaise Ndembi, Vittorio Colizzi, Carla Montesano, Carlo-Federico Perno, Francesca Ceccherini-Silberstein, Joseph Fokam   +17 more
doaj   +1 more source

The comparative effectiveness of methylprednisolone versus dexamethasone on in-hospital mortality in patients with severe or critical COVID-19: a retrospective observational study

Therapeutic Advances in Infectious Disease
Background: Studies comparing the effectiveness of dexamethasone versus methylprednisolone for treating severe-to-critical COVID-19 have produced conflicting results.
Abdullah Wagley, Samar Fatima, Safia Awan, Maheen Zakaria, Aleena Arshad, Farah Khalid, Noreen Nasir, Masooma Aqeel, Nosheen Nasir   +8 more
doaj   +1 more source

Ensitrelvir as a novel treatment option for mild-to-moderate COVID-19: a narrative literature review

Therapeutic Advances in Infectious Disease
To address the coronavirus disease 2019 (COVID-19) pandemic, several antiviral agents targeting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been developed for clinical use.
Hiroshi Mukae, Hiroshi Yotsuyanagi, Norio Ohmagari, Yohei Doi, Masaya Yamato, Takumi Imamura, Hiroki Sakaguchi, Takao Sanaki, Takuhiro Sonoyama, Yuko Tsuge, Takeki Uehara   +10 more
doaj   +1 more source

Comparative Efficacy of Topical Pyrethroids and Benzoyl Peroxide for Treating Chorioptic Mange in Spanish-Breton Horses

Journal of Parasitology Research
Chorioptic mange is a challenging condition to treat due to the superficial locations of the nonhematophagous mite Chorioptes bovis, and while topical acaricides are recommended, the clinical feature relapses are frequent.
Juan D. Carbonell, Nélida Fernández, Manuel J. Escobar, Maria T. Álvarez, Lucia Sánchez, Aday Hernández, Aránzazu Meana   +6 more
doaj   +1 more source