Results 31 to 40 of about 58,518 (50)

Recent update of proton beam therapy for hepatocellular carcinoma: a systematic review and meta-analysis [PDF]

Journal of Liver Cancer
Backgrounds/Aims Although access to proton beam therapy (PBT) is limited worldwide, its use for the treatment of hepatocellular carcinoma (HCC) is gradually increasing with the expansion of new facilities.
Sun Hyun Bae, Won Il Jang, Hanna Rahbek Mortensen, Britta Weber, Mi Sook Kim, Morten Høyer   +5 more
doaj   +1 more source

Diagnostic utility of prostate health index density prior to MRI-ultrasound fusion targeted biopsy

Exploration of Targeted Anti-tumor Therapy
Aim: Prostate biopsy can be prone to complications and thus should be avoided when unnecessary. Although the combination of magnetic resonance imaging (MRI), the prostate health index (PHI), and PHI density (PHID) has been shown to improve detection of ...
Benjamin H. Press, Soum D. Lokeshwar, Lindsey Webb, Ghazal Khajir, Shayan Smani, Olamide Olawoyin, Mursal Gardezi, Syed N. Rahman, Michael S. Leapman, Preston C. Sprenkle   +9 more
doaj   +1 more source

Development and validation of a machine learning-based prognostic model for IgA nephropathy with CKD stage 3 or 4

Kidney Diseases
Introduction: Immunoglobulin A nephropathy (IgAN) patients with lower estimated glomerular filtration rate (eGFR) and higher proteinuria are at a higher risk for end-stage kidney disease (ESKD) and their prognosis is still unclear.
Zixian Yu, Xiaoxuan Ning, Yunlong Qin, Yan Xing, Qing Jia, Jinguo Yuan, Yumeng Zhang, Jin Zhao, Shiren Sun   +8 more
doaj   +1 more source

Exploring the therapeutic potential of lipid-based nanoparticles in the management of oral squamous cell carcinoma

Exploration of Targeted Anti-tumor Therapy
Oral squamous cell carcinoma (OSCC) is a highly malignant and invasive tumor with significant mortality and morbidity. Current treatment modalities such as surgery, radiotherapy, and chemotherapy encounter significant limitations, such as poor targeting,
Anis Ahmad Chaudhary, Mohammad Fareed, Salah-Ud-Din Khan, Lina M. Alneghery, Mohammed Aslam, Arockia Alex, Md. Rizwanullah   +6 more
doaj   +1 more source

Role of exosomes in transforming growth factor-β-mediated cancer cell plasticity and drug resistance [PDF]

Exploration of Targeted Anti-tumor Therapy
Transforming growth factor-β (TGF-β) is a multifunctional molecule with a dual role in carcinogenesis. Recent studies have demonstrated its various effects on cancer-related processes.
Tatiana Ruksha, Nadezhda Palkina
doaj   +1 more source

The Bone-Vascular Axis: A Key Player in Chronic Kidney Disease Associated Vascular Calcification

Kidney Diseases
Background: The bone-vascular axis plays a key role in the pathogenesis of vascular calcification (VC) in patients with chronic kidney disease (CKD). Understanding and managing the role of the bone-vascular axis in CKD-mineral and bone disorder (CKD-MBD)
Yingjing Shen, Chen Yu
doaj   +1 more source

Interactive effect of 25-hydroxyvitamin D3 and M-type phospholipase A2 receptor gene polymorphism on the progression of idiopathic membranous nephropathy

Linchuang shenzangbing zazhi
Objective To explore the interaction between 1,25-hydroxyvitamin D3 [25-（OH）D3] and M-type phospholipase A2 receptor 1 （PLA2R1） gene polymorphism in the progression of idiopathic membranous nephropathy （IMN）.
Xian-li Huang, Fei-ya Wen, Yan Hao
doaj   +1 more source

Research advances of proteolysis targeting chimeras for acute kidney injury

Linchuang shenzangbing zazhi
Acute kidney injury （AKI） is a diverse group of renal diseases characterized by a dramatic decline in renal function. Not only AKI has a high mortality rate， but also poor renal adaptation or incomplete repair after acute phase may also lead to renal ...
Jun-dan Jia, Yu-feng Qiao
doaj   +1 more source

Effect of ocular hypertension on the levels of glycation products in anterior eyes tissues in streptozotocin-induced diabetes

Journal of Ophthalmology, 2016
V.R.Yurevich
doaj   +1 more source

Use of bromfenac 0.09% (Broksinak) in the complex therapy for HLA-B27-associated anterior uveitis

Journal of Ophthalmology
Background: There is still no consensus among ophthalmologists as to whether the prolonged use of topical bromfenac 0.09% is feasible in therapy for acute uveitis.
Oleksandra Zborovska
doaj   +1 more source