Results 11 to 20 of about 67,740 (99)

Function of hsa_circ_0006646 as a competing endogenous RNA to promote progression in gastric cancer by regulating the miR-665–HMGB1 axis

Journal of Gastrointestinal Oncology, 2023
Background Mounting evidences indicate that circular RNAs (circRNAs) are a novel class of non-coding RNAs and play vital roles in the tumorigenesis and aggressiveness including gastric cancer (GC).
Jingkun Qin, S. Zhen, Jiali Wang, Wei-Biao Lv, Yan Zhao, Y. Duan, Tianxu Liu, Lei Feng, Guiying Wang, Lihua Liu   +9 more
semanticscholar   +1 more source

Knockdown of Circ_0037658 Alleviates IL-1β-Induced Osteoarthritis Progression by Serving as a Sponge of miR-665 to Regulate ADAMTS5

Frontiers in Genetics, 2022
Background: Osteoarthritis (OA) is a chronic musculoskeletal degeneration disease which brings great pain to patients and a tremendous burden on the world’s medical resources.
Ningbo Li, Yongsheng Wang, X. Wu
semanticscholar   +1 more source

Sevoflurane Inhibits Metastasis in Hepatocellular Carcinoma by Inhibiting MiR-665-Induced Activation of the ERK/MMP Pathway

Cell Transplantation, 2022
Recent evidence has indicated that inhalational anesthetics may affect the growth and malignant potential of tumor cells and ultimately influence tumor recurrence after surgery.
Xiaoyan Zhu, Chuchu Peng, Zhiyong Peng, R. Chang, Q. Guo   +4 more
semanticscholar   +1 more source

Circ_0078767 Inhibits the Progression of Non-Small-Cell Lung Cancer by Regulating the GPX3 Expression by Adsorbing miR-665

International Journal of Genomics, 2022
Non-small-cell lung cancer (NSCLC) is one of the most serious cancers. The circular RNA_0078767 (circ_0078767) expression was decreased in NSCLC tissues. However, the molecular mechanism of circ_0078767 remains unknown.
Xiting Liu, Ze Chen, Yuqiang Wu, F. Gu, Dong Yan, Lei Yang, Qin Ma, Caihong Fu   +7 more
semanticscholar   +1 more source

Inhibition of microRNA-665 Alleviates Septic Acute Kidney Injury by Targeting Bcl-2

Journal of Healthcare Engineering, 2022
Sepsis can easily cause acute kidney injury (AKI) and seriously endanger human health. This article aims to investigate and study the role of microRNA-665 (miR-665) in septic AKI and the underlying molecular mechanism.
Yongjie Qi, Yue Han, Chen Chen, Y. Xue, N. Jiao, Xuejun Li   +5 more
semanticscholar   +1 more source

Circ_0001206 regulates miR‐665/CRKL axis to alleviate hypoxia/reoxygenation‐induced cardiomyocyte injury in myocardial infarction

ESC Heart Failure, 2022
Myocardial infarction (MI) is a type of cardiovascular disease caused by myocardial necrosis. Growing evidences have suggested that circular RNAs (circRNAs) play crucial roles in cardiac hypoxia/reoxygenation (H/R)‐induced injury of MI.
Dongmei Wang, Limei Tian, Yan Wang, Xiaoli Gao, Hanbo Tang, J. Ge   +5 more
semanticscholar   +1 more source

Impact of the number of previous embryo implantation failures on IVF/ICSI-ET pregnancy outcomes in patients younger than 40 years: a retrospective cohort study

Frontiers in Endocrinology, 2023
ObjectiveThe objective of this study was to examine the influence of repeated embryo implantation failures on pregnancy outcomes among patients under 40 years of age undergoing in vitro fertilization/intracytoplasmic sperm injection embryo transfer (IVF ...
Yuan Fang, Yuan Fang, Fan Jingjing, Fan Jingjing, Cheng Tiantain, Cheng Tiantain, Xie Huanhuan, Xie Huanhuan, He Qiaohua, He Qiaohua   +9 more
doaj   +1 more source

Hsa_hsa_circ_0081069 promotes the progression of colorectal cancer through sponging miR‐665 and regulating E2F3 expression

Journal of clinical laboratory analysis (Print), 2022
Circular RNAs (circRNAs) have been implicated in the initiation and development of various cancers. This study explored the potential contribution of hsa_hsa_circ_0081069 in the progression of colorectal cancer (CRC).
Jingjing Xie, Danjuan Jin, Jinyin Xu, Fei Yang, Jianying Jin   +4 more
semanticscholar   +1 more source

Neuropeptide hormone bursicon mediates female reproduction in the whitefly, Bemisia tabaci (Hemiptera: Aleyrodidae)

Frontiers in Endocrinology, 2023
Bursicon, a neuropeptide hormone comprising two subunits-bursicon (burs) and partner of burs (pburs), belongs to the cystine-knot protein family. Bursicon heterodimers and homodimers bind to the lucine-rich G-protein coupled receptor (LGR) encoded by ...
Hao Yu, Bin Yang, Liuhao Wang, Sijia Wang, Kui Wang, Qisheng Song, Hongwei Zhang   +6 more
doaj   +1 more source

Exosomal lncRNA SCIRT/miR-665 Transferring Promotes Lung Cancer Cell Metastasis through the Inhibition of HEYL

Journal of Oncology, 2021
Lung cancer remains the leading cause of cancer-related death worldwide. Recently, extracellular vesicles such as exosomes have attracted considerable interest both as a source for theranostic biomarkers and an essential participant in lung cancer ...
Zhengyang Wang, Minmin Lin, Lulu He, H. Qi, Jing Shen, K. Ying   +5 more
semanticscholar   +1 more source