Results 11 to 20 of about 65,509 (99)

MicroRNA-665-3p exacerbates nonalcoholic fatty liver disease in mice

Bioengineered, 2022
Oxidative stress and chronic inflammation are major culprits of nonalcoholic fatty liver disease (NAFLD). MicroRNA-665-3p (miR-665-3p) is implicated in regulating inflammation and oxidative stress; however, its role and molecular basis in NAFLD remain ...
Yuanjie Yu, T. Tian, Shiyun Tan, Peng-bo Wu, Yitian Guo, Ming Li, Mengjun Huang   +6 more
semanticscholar   +1 more source

Development of a High-Density 665 K SNP Array for Rainbow Trout Genome-Wide Genotyping

bioRxiv, 2022
Single nucleotide polymorphism (SNP) arrays, also named « SNP chips », enable very large numbers of individuals to be genotyped at a targeted set of thousands of genome-wide identified markers.
M. Bernard, Audrey Dehaullon, Guangtu Gao, Katy Paul, H. Lagarde, M. Charles, M. Prchal, J. Danon, L. Jaffrelo, C. Poncet, P. Patrice, P. Haffray, E. Quillet, M. Dupont-Nivet, Y. Palti, D. Lallias, F. Phocas   +16 more
semanticscholar   +1 more source

Function of hsa_circ_0006646 as a competing endogenous RNA to promote progression in gastric cancer by regulating the miR-665–HMGB1 axis

Journal of Gastrointestinal Oncology, 2023
Background Mounting evidences indicate that circular RNAs (circRNAs) are a novel class of non-coding RNAs and play vital roles in the tumorigenesis and aggressiveness including gastric cancer (GC).
Jingkun Qin, S. Zhen, Jiali Wang, Wei-Biao Lv, Yan Zhao, Y. Duan, Tianxu Liu, Lei Feng, Guiying Wang, Lihua Liu   +9 more
semanticscholar   +1 more source

Circ_0104700 contributes to acute myeloid leukemia progression by enhancing MCM2 expression through targeting miR-665

Hematology, 2023
Objective Acute myeloid leukemia (AML) is a common blood cancer associated with poor prognosis and high mortality. In this study, we investigated the role and underlying mechanism of action of circ_0104700 in the pathogenesis of AML. Methods Circ_0104700
Kang Chen, Xiaohan Ning, Xiaohong Yan, Lingling Song   +3 more
semanticscholar   +1 more source

Knockdown of Circ_0037658 Alleviates IL-1β-Induced Osteoarthritis Progression by Serving as a Sponge of miR-665 to Regulate ADAMTS5

Frontiers in Genetics, 2022
Background: Osteoarthritis (OA) is a chronic musculoskeletal degeneration disease which brings great pain to patients and a tremendous burden on the world’s medical resources.
Ningbo Li, Yongsheng Wang, X. Wu
semanticscholar   +1 more source

The Association Between Leucine and Diabetic Retinopathy in Different Genders: A Cross-Sectional Study in Chinese Patients With Type 2 Diabetes

Frontiers in Endocrinology, 2022
ObjectiveTo explore the association between serum leucine (leu) and diabetic retinopathy (DR) in patients with type 2 diabetes (T2D) and then to analyze the influence of gender on the association.MethodThe electronic medical records of 1,149 T2D patients
Shen Li, Bing Huang, Ming-Li Liu, Xue-Ting Cui, Yun-Feng Cao, Yun-Feng Cao, Zheng-Nan Gao   +6 more
doaj   +1 more source

Composite pheochromocytoma/ paraganglioma-ganglioneuroma: analysis of SDH and ATRX status, and identification of frequent HRAS and BRAF mutations

Endocrine Connections, 2021
Introduction: Composite pheochromocytoma/paraganglioma (CP) is a rare neoplasm with most cases presented as single reports. Little is known about its pathogenesis and relationship with ordinary pheochromocytoma (PCC) or paraganglioma (PGL).
Jingci Chen, Yan Wu, Pengyan Wang, Huanwen Wu, Anli Tong, Xiaoyan Chang   +5 more
doaj   +1 more source

Sevoflurane Inhibits Metastasis in Hepatocellular Carcinoma by Inhibiting MiR-665-Induced Activation of the ERK/MMP Pathway

Cell Transplantation, 2022
Recent evidence has indicated that inhalational anesthetics may affect the growth and malignant potential of tumor cells and ultimately influence tumor recurrence after surgery.
Xiaoyan Zhu, Chuchu Peng, Zhiyong Peng, R. Chang, Q. Guo   +4 more
semanticscholar   +1 more source

The probability of the influence of professional chemical factors on the development of hypothyroidism and other lesions of the human body

Mìžnarodnij Endokrinologìčnij Žurnal, 2020
Background. The purpose is to present clinical observations of diseases of workers in individual industries, where a priori there was an effect of various production chemical factors that caused damage to the cardiovascular system such as coronary heart ...
A.I. Voloshin, T.A. Ilashchuk, L.A. Voloshina, I.V. Pankiv, V.S. Yuzvenko   +4 more
doaj   +1 more source

Investigation Into the Predictive Potential of Three-Dimensional Ultrasonographic Placental Volume and Vascular Indices in Gestational Diabetes Mellitus

Frontiers in Endocrinology, 2021
BackgroundThe use of ultrasonography in pregnancies complicated with gestational diabetes mellitus (GDM) can vary according to clinical practice. This study aims to compare the changes of placental volume (PV) and vascular indices measured by three ...
Zhenyan Han, Yuan Zhang, Xuelan Li, Xuelan Li, Wei-Hsiu Chiu, Wei-Hsiu Chiu, Yuzhu Yin, Hongying Hou   +7 more
doaj   +1 more source